Ch 8: Dyslipidema et al. Flashcards
What is also called hyperlipidemia because increased blood levels of lipoproteins accompany increased blood lipid levels. It is an abnormal level of lipids in the blood associated with atherosclerosis, myocardial infarction, stroke, peripheral arterial occlusive disease.
Dyslipidemia
What is the difference between primary and secondary dyslipidemia?
Primary Dyslipidemia—genetic or familial
Secondary dyslipidemia—diabetes, alcoholism, hypothyroidism, obesity, medications
What is metabolic syndrome?
group of cardiovascular risk factors linked with obesity.
How long should a person fast when testing for triglycerides?
12 hours
What does hypercholesterolemia equal?
hyperlipoproteinemia
Total serum cholesterol (mg/dL)- ADULTS:
Normal or desirable ???
Normal or desirable LESS THAN 200
High 240 or above
LDL cholesertol (mg/dL) ADULTS:
Optimal= LESS THAN 100
High= 160-189
Protective level of HDL cholesterol (mg/dL) ???
High= more than 60
Protective level-= 40-60
Low= LESS THAN 40
Triglycerides (mg/dL)???
Normal or desirable= LESS THAN 150
What do statins decrease? (4 things)
Decrease total serum cholesterol, LDL cholesterol, VLDL cholesterol and triglycerides.
How long does it take for statins to reduce LDL cholesterol?
2 weeks
What is Most effective and most widely used drug class for dyslipidemia
Atorvastatin: aka Lipitor/ HMG-CoA
What should you not take statins with?
Grapefruit juice!
What is a Vitamin that decreases LDL and increases HDL
Niacin
What is the Most effective drug for increasing HDL?
Niacin (also, Use with statin lowers serum LDL cholesterol more than either drug alone)
