Ch. 4 Flashcards

Cell Proliferation and Tissue Regeneration and Repair

1
Q

Skin assessment of African American client, notes of the healed wound on the leg but excess of scar tissue. The nurse documents this as which of the following?

A

Keloid p. 81

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2
Q

large leg wound…notes client’s past medical history includes diabetes, chronic atrial fibrillation, asthma, and neuropathy. Which one has the greatest potential to negatively impact the healing of the client’s wound?

A

Diabetes p.84

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3
Q

Some tissues, such as the mucosal surface of the GI tract have cells that are capable of cell division and serve as reserve source for specialized cells. Which term describes these cells?

A

Stem cells p.72, 73, 76

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4
Q

When caring for a client with a wound that is healing by primary intention the nurse recognized which of these best describes this type of wound?

A

Surgical incision p.79

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5
Q

Client w/ hypovolemic shock secondary to penetrating multiple trauma. post-op which factors places the client at risk for poor wound healing?

A

Tissue hypoxia p. 83-84

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6
Q

select the statement that best describes stem cells

A

Undifferentiated cells of continuously dividing tissues that have the capacity to generate multiple cell types. p. 73

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7
Q

Cigarette smoker had a mass removed from the lung. He will have a good amount of fibrosis developed in the surgical area. Fibrosis is described as:

A

Result in replacement tissue in the form of connective (fibrous) tissue which leads to scar formation or fibrosis of the lung. p. 71

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8
Q

Researchers wish to reactive the cell cycle in nonproliferating cells to assist the body to repair tissue. To reactivate the cycle, which substance will the researchers need to remove from the cell?

A

CDK inhibitors P.73

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9
Q

While reviewing the phases of wound healing, the students note that the first cells to arrive after injury are the:

A

neutrophils p.80

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10
Q

Describe the process resulting in specialized cells.

A

Differentiation p. 71-72

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11
Q

which stage of a cell’s life cycle is where the preparation of mitosis occurs?

A

G1 p.72-73

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12
Q

An infected burn of the arm is an example of wound healing by primary or secondary intention?

A

secondary p. 79-80

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13
Q

Post-op patient documents that the surgical incision is healing by which of the following?

A

primary intention p. 79

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14
Q

To promote wound healing, which nutrient does the nurse encourage to consume?

A

Vit. C p.81

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15
Q

What happens if, in the process of going through the cell cycle, a cell is damaged?

A

There are built in checkpoints in the cell cycle to allow for defects to be edited and repaired p. 72

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16
Q

An infected foot wound on 45y/o patient w/ peripheral vascular disease may be treated with what oxygen delivery?

A

Hyperbaric Oxygen p. 83-84

17
Q

An injury from 3 days ago is anticipated to be in what phase of healing?

A

Proliferative p.80

18
Q

A client with a torn rotator cuff has been asked by his dr, to consider allowing transplantation of his own stem cells into his area of injury. This is an example of:

A

Therapeutic cloning p.76

19
Q

Which responsibility of the extracellular matrix (ECM) is most accurate?

A

The ECM provides scaffolding for tissue renewal. p. 77

20
Q

Strength in the healing wound site is developed based on which substance being available?

A

Collagen synthesis p. 79

21
Q

Phases of wound healing?

A

Inflammatory
Proliferative
Remodeling
p.80

22
Q

Continuously dividing cells divide and replicate like:

A

cells in mouth
cells on surface of skin
cells lining GI tract
p.73

23
Q

During synthesis phase of cell cycle, the cell is:

A

undergoing a period of DNA synthesis and replication of chromosomes p. 74

24
Q

Presence of granulation tissue at a wound site is identified by:

A

Red, moist tissue p.78

25
Q

What do you call it when a cell undergoes a process of increasing cell number by mitotic division?

A

Cell proliferation P. 71-72

26
Q

Growth of new vessels into the damaged area is known as:

A

Angiogenesis p. 76

27
Q

Metalloproteinase requires which mineral before degradation of collagen occurs?

A

Zinc p.79

28
Q

Which substance can cleave collagen fibers to facilitate cell migration through tissues?

A

Protease p. 52

29
Q

Tissue repair through regeneration occurs in which cells?

A

Parenchymal p. 71, 72, 76

30
Q

How does hyperbaric oxygen treatment enhance wound healing?

A

promotion of angiogenesis p. 83-84