Ch. 33 - Aerobic, non-fermentative, G-b Flashcards

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1
Q

Psuedomonas characteristics

A
motile G-b
OXI +
capsule (mucoid)
*loves moisture* (hospital environment)
Opportunistic
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2
Q

Pseudomonas pathogenesis

A
  • adhesins (flagella and pili)
  • alginate
  • LPS
  • toxins & enzymes - exotoxin A, pyocyanin, pyoverdin, Las A andB, Alkaline protease, phospholipase C, Exoenzymes S - and T
  • antibiotic resistance
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3
Q

Pseudomonas Disease

A
  • *Pulmonary
  • Skin and soft tissue
  • Folliculitis
  • Osteochondritis
  • UTI
  • External Otitis
  • Malignant External Otitis
  • Chronic otitis media
  • Eye infections
  • Bacteremia
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4
Q

Pseudomonas aeruginosa characteristics

A
G-b 
OXI +
Motile
SAe
green colonies
grape-like odor
flat, b-hem colonies
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5
Q

Pseud. aeruginosa diseases

A

Pulmonary

Chronic otitis media

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6
Q

Exotoxin A (Pseud)

A

disrupts protein synthesis

cause of dermatonecrosis in burn pts.

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7
Q

pyocyanin (pseud)

A

catalyzes H2O2 and superoxide production

stimulates IL-8 –> neutrophils

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8
Q

pyoverdin (pseud)

A

binds iron for metabolism

regulates exotoxin A secretion

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9
Q

Las A and Las B (pseud)

A

degrade elastin in tissues

degrade complement

spread of infection

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10
Q

Alkaline protease (pseud)

A

tissue destruction and spread

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11
Q

Phospholipase C (pseud)

A

degrades lipids and lecithin–> tissue destruction

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12
Q

Pseud. antibiotic resistance

A

mutation of pore proteins restrict antibiotic entry into cell

resistance to different classes of antibiotic at the same time

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13
Q

Burkholderia cepacia

A
G-b
OXI +
Aerobic
opportunistic; low virulence 
colonize resp. compromised (CF)
UTI, septicemia (catheters)
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14
Q

Burkholderia pseudomallei

A
G-b
OXI +
Aerobic
opportunistic
Melioidosis
Inhalation (pulmonary disease and sepsis)
cutaneous inoculation (lymphadenitis, fever, malaise)
biological warfare
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15
Q

Stenotrophomonas maltophilia

A
G-b 
OXI - *
NFB
Aerobic 
Nosocomial
Bacteremia and pneumonia (device associated) 
^ death rate
^ resistant to antibiotics
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16
Q

Acinetobacter

A
G-cb
Non-motile
OXI -
Opportunistic (device and broad-spectrum antibiotics) 
Human skin
GLUC oxidizing and non-oxidizing
Resp., UTI, wound, septicemia
Antibiotic resistance
17
Q

Moraxella catarrhalis

A
G-dc
OXI +
Aerobic
Produces beta lactamase
Bronchitis and bronchopneumonia (esp. resp. compromised)