Ch 31: Adrenergic Blocking Antagonists

Question 1

adrenergic-receptor-site specificity

Answer 1

a drug’s affinity for only adrenergic receptor sites; certain drugs may have affinity for only alpha or only beta adrenergic receptor sites

Question 2

alpha1- selective adrenergic blocking agents

Answer 2

drugs that block the postsynaptic alpha1-receptor sites, causing a decrease in vascular tone and a vasodilation that leads to a fall in blood pressure; do not block the presynaptic alpha2-receptor sites, and therefore the reflex tachycardia that accompanies a fall in BP does not occur

Question 3

beta-adrenergic blocking agent

Answer 3

drugs that, at therapeutic levels, selectively block the beta-receptors of the sympathetic nervous system

Question 4

beta1-selective adrenergic blocking agents

Answer 4

drugs that, at therapeutic levels, specifically block the beta1-receptors in the sympathetic nervous system while not blocking the beta2-receptors and resultant effects on the respiratory system

Question 5

bronchodilation

Answer 5

relaxation of the muscles in the bronchi, resulting in a widening of the bronchi; an effect of sympathetic stimulation

Question 6

pheochromocytoma

Answer 6

a tumor of the chromaffin cells of the adrenal medulla that periodically releases large amounts of norepinephrine and epinephrine into the system with resultant severe hypertension and tachycardia

Question 7

sympatholytic

Answer 7

a drug that lyses, or blocks, the effects of the sympathetic nervous system