ch 31 Flashcards
50:50 mix of dextroamphetamine and levoamphetamine
amphetamine
amphetamines CNS
wakefulness alertness reduce fatigue elevate mood augment self confidence and initiative
task performance that has been reduced by fatigue or boredom improves
supress appetite and perception of pain
amphetamines works on what neurotransmitter
NE - most effects are due to this
and dopamine
heart and amphetamines
increased HR and BP
dysrhythmias, angina and HTN with preexisting heart condition
tolerance and amphetamines
regular use - tolerance can develop
physical dependence amphetamines
chronic use can produce physical dependence
amphetamines and abuse -
potential for abuse due to euphoria
amphetamines is a schedule
II
adverse effect amphetamines CNS
insomnia
restlessness
adverse effects amphetamines weight
weight loss secondary to anorexia
adverse effects amphetamines psychosis
excessive use produces a state of paranoid psychosis characterized by hallucinations and paranoid delusions
looks like schitzophrenia
what med can be used for amphetamine induced psychosis -
DA receptor blocking agent - Haloperidol
after drug is withdrawn the psychosis usually resolves in a week
a disorder characterized by daytime somnolence and uncontrollable attacks of sleep
narcolepsy
what can you give in narcolepsy to promote wakefulness
amphetamines
Methylphenidate (Ritalin)
used in
works like
schedule
works similarly to amphetamines
schedule II
ADHD and narcolepsy
Dexmethylphenidate (Focalin) is used in
ADHD
Caffeine is used in
neonatal apnea
promoting wakefulness
Modafinil (Provigil) is used in
promoting wakefulness associated with
narcolepsy
shift-work sleep disorder
Obstructive sleep hypopnea syndrome