Ch. 3 Studying the Damaged Brain Flashcards

1
Q

Angiography

A

An imaging method used to evaluate the CIRCULATORY system in the brain.

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2
Q

Block Design Experiment

A

An experiment in which the recorded neural activity is integrated over a “block” of time during which the participant is either presented a stimulus or performs a task. The recorded activity pattern is then compared to other blocks that have been recorded while doing the same task or stimulus, a different task or stimulus, or nothing at all.

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3
Q

Blood Oxygen Level-Dependent (BOLD)

A

When neurons become more active, this triggers an increase in the amount of oxygenated blood entering local capillaries in the tissue.

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4
Q

Brain Graph

A

A visual model of the connections within some part of the nervous system.

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5
Q

Brain Lesion

A

Structural damage to the white or gray matter of the brain.

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6
Q

Cerebral Vascular Accident

A

A rapid loss of brain function due to a compromise in the blood supply to the brain secondary to arterial occlusion or hemorrhage.

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7
Q

Cognitive Psychology

A

The branch of psychology that studies how the mind is internally represents the external world and performs the mental computations required for all aspects of thinking.

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8
Q

Computed Tomography (CT or CAT)

A

A noninvasive neuroimaging method that provides images of internal structures such as the brain. CT is an advanced version of the conventional X-ray.
CT allows for the reconstruction of three-dimensional space from the compressed two-dimensional images through computer algorithms.

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9
Q

Deep-Brain Stimulation (DBS)

A

The electrical stimulation of brain structures via an implanted electrode. Stimulation of the subthalamic nucleus, one of the nuclei of the basal ganglia, is used as a treatment for Parkinson’s disease.

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10
Q

Degenerative Disorder

A

Disorders or diseases, either genetic or environmental, in which the function or structure of the affected tissues will continue to deteriorate over time.

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11
Q

Diffusion Tensor Imaging (DTI)

A

A neuroimaging technique employed using an MRI scanner that allows white matter pathways in the brain to be imaged.

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12
Q

Double Dissociation

A

A method used to develop functional models of mental and/or neural processes. Evidence of a double dissociation requires a minimum of two groups and two tasks.

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13
Q

Electrocortogram (ECoG)

A

A method to record electrical activity from the CEREBRAL CORTEX by placing ELECTRODES directly on the surface of the brain, either outside the dura or beneath it.

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14
Q

Electroencephalography (EEG)

A

A technique to measure the electrical activity of the brain. In EEG, surface recordings are made with electrodes places on the scalp. The EEG signal includes endogenous changes in electrical activity (due to changes in arousal) as well as those triggered by specific events (stimuli or movements)

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15
Q

Event-Related Design

A

A paradigm used in fMRI studies in which the BOLD response can be time-locked to particular stimuli or responses. Such designs require using delays or temporal variation in order to isolate the response to these events.

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16
Q

Event-Related Potential (ERP)

A

A change in electrical activity that is time-locked to specific events such as the presentation of a stimulus or the onset of a response. When the events are repeated many times, averaging the EEG signals reveals the relatively small changes in neural activity triggered by these events.

17
Q

Functional Magnetic Resonance Imaging (fMRI)

A

A neuroimaging method that utilizes MRI to track blood flow changes in the brain that are thought to be correlated with local changes in neuronal activity.

18
Q

Knockout Procedure

A

A technique for creating a genetically altered version of a species. In the knockout species, specific genes are altered or eliminated. This can be used to to study behavioral changes occurring in animals that have developed without the targeted gene or to see how genes code the development of the nervous system.

19
Q

Magnetic Resonance Imaging (MRI)

A

A neuroimaging technique that exploits the magnetic properties of organic tissue.

20
Q

Magnetoencephalography (MEG)

A

A measure of the magentic signals generated by the brain. MEG can be used in an event-related manner similar to ERP studies, with similar temporal resolution. The spatial resolution, in theory, can be superior with MEG because magnetic signals are minimally distorted by organic tissue such as the brain or skull.

21
Q

Multiunit Recording

A

A physiological procedure in which an array of electrodes is inserted in the brain such that they activity of many cells can be recorded simultaneously.

22
Q

Neural Network

A

Computer model in which processing is distributed over units whose inputs and outputs represent specific features.

23
Q

Neurophysiology

A

The study of the physiological processes of the nervous system.

24
Q

Optogenetics

A

A procedure in which a genetic manipulation is performed that will result in the expression of a photosensitive protein.The experimenter can the activate the neurons by exposing the tissue to light.

25
Q

Pharmacological Studies

A

Experimental method in which the independent variable involves the administration of a chemical agent of drug.

26
Q

PiB

A

A radioactive compound that is used as a tracer in PET studies to label beta-amyloid.

27
Q

Positron Emission Tomography (PET)

A

A neuroimaging method that measures METABOLIC activity or BLOOD FLOW changes in the brain by monitoring the distribution of a radioactive tracer.

28
Q

Receptive Field

A

The area of external space within which a stimulus that must be presented in order to activate a cell.

29
Q

Regional Cerebral Blood Flow (rCBF)

A

The distribution of the brains’s blood supply, which can be measured with various imaging techniques.

30
Q

Retinotopic

A

Referring to a topographic map of visual space across a restricted region of the brain.

31
Q

Simulation

A

A method used in computer modeling to mimic a certain behavior or process. This program can then be used to generate new predictions.