Ch. 24- Kidney Structure and Function Flashcards

1
Q

What are the kidneys functions?

A
  • Filter blood
  • Remove Water-soluble wastes
  • Help control BP and blood composition
  • Help maintain RBC and calcium levels
  • Help maintain acid-base balance
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2
Q

What is the GFR a standard to determine?

A

Kidney Failure

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3
Q

In relation to the GFR approximately how many mL/min can be filtered?

A

125mL/min

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4
Q

Where is the glomerulus located?

A

Between the afferent and efferent arterioles.

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5
Q

The Glomerulus is influenced by what?

A

Sympathetic Nervous System and Sensitive to angiotensin II (potent vasoconstrictor)

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6
Q

In relations to GFR how do the afferent and efferent arterioles respond to the sympathetic nervous system and angiotensin II?

A

By Vasoconstricting or Vasodilating.

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7
Q

A reduction of renal blood flow happens and a decrease in GFR when which arterioles do what?

A

Afferent arteriole vasoconstricts.

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8
Q

An increase in resistance to renal blood outflow increases glomerular pressure and GFR how?

A

Efferent arteriole vasoconstricts.

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9
Q

How would GFR change if there was an increase in BP?

A

efferent arterioles vasoconstrict

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10
Q

How would GFR change if there was a decrease in BP?

A

Afferent arteriole vasoconstricts.

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11
Q

Which Renal structure reabsorbs water?

A

Proximal Tubule

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12
Q

Which pathway turns on the Na+/K+ ATPase in the distal tubule?

A

Renin-Angiotension-Aldosterone Pathway

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13
Q

The Renin-Angiotension-Aldosterone Pathway cause Na+ and water to be what? causing what?

A

Reabsorbed.

  • Raising blood volume
  • No change to blood osmolarity.
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14
Q

What is secreted with the Renin-Angiotensin-Aldosterone pathway? causing what?

A

K+ , lowers blood K+

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15
Q

ANP (Atrial natriuretic peptide) is made by what?

A

Overstretched atria.

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16
Q

BNP (B-type natriuretic peptide) is made by what?

A

Overworked ventricles.

17
Q

ANP and BNP both cause what?

A

Kidneys to stop reabsorbing NaCl

18
Q

What is a product of creatine metabolism in muscles?

A

Serum Creatinine

19
Q

Serum Creatinine reflects what?

A

GFR

20
Q

What does BUN stand for?

A

Blood urea nitrogen.

21
Q

What is a byproduct of protein metabolism?

A

BUN

22
Q

Where is BUN eliminated from?

A

Kidneys.

23
Q

What is BUN influenced by?

A
  • Protein intake
  • GI bleeding
  • Hydration status
24
Q

Which lab value is less specific to renal insufficiency?

A

BUN