Ch. 14 - Mendel & the Gene Idea Flashcards
A heritable feature that varies among individuals
Character
Each variant for a character
Trait
Plants who, over many generations of self-pollination, have produced only the same variety of the parental plant
True-breeding
The mating (or crossing) of two true-breeding varieties for different traits
Hybridization
Parental generation
P generation or P1 generation
First filial generation
F1 generation
Second filial generation
F2 generation
Alternate versions of a gene
Alleles
The allele that controls the phenotype of a heterozygote
Dominant allele
The allele in a heterozygote with no noticeable phenotypic effects
Recessive allele
The two alleles for a heritable character segregate during gamete formation and end up in different gametes
Law of Segregation
A handy diagrammatic device for predicting the allele composition of offspring from a cross between individuals of known genetic makeup
Punnett Square
An organism that has a pair of identical alleles for a gene encoding a character
Homozygote
Having a pair of identical alleles for a gene encoding a character
Homozygous
An organism that has two different alleles for a gene
Heterozygote
Having two different alleles for a gene
Heterozygous
An organism’s appearance or observable traits
Phenotype
An organism’s genetic makeup
Genotype
Breeding an organism of unknown genotype with a recessive homozygote
Testcross
All the F1 progeny produced in crosses of true-breeding parents following one trait
Monohybrids
A cross between heterozygotes for one trait
Monohybrid cross
The F1 plants produced in a cross between two true-breeding varieties differing for two traits being observed
Dihybrids
A cross between dihybrids
Dihybrid cross
Two or more genes assort independently - that is, each pair of alleles segregates independently of any other pair of alleles - during gamete formation
Law of Independent Assortment
To determine the probability of multiple events, multiply the probability of one event by the other(s) to see the probability of the total event
Multiplication rule
The probability that any one of two or more mutually exclusive events will occur is calculated by adding their individual probabilities
Addition rule
Genes having multiple phenotypic effects
Pleiotropy
Characters that vary along a continuum
Quantitative characters
Degree of dominance in which one allele completely controls the phenotype of the heterozygote
Complete dominance
In which neither allele shows through in the heterozygote, but a new, intermediate phenotype does
Incomplete dominance
Degree of dominance in which both alleles each affect the phenotype in separate, distinguishable ways
Codominance
An inherited disease in humans that expresses incomplete dominance; the brain cells of a homozygote cannot metabolize certain lipids
Tay-Sachs Disease
The phenotypic expression of a gene at one locus alters that of a gene at a second locus
Epistasis
An additive effect of two or more genes on a single phenotypic character
Polygenic inheritance
Meaning that many factors, both genetic and environmental, collectively influence phenotype
Multifactorial
A family tree describing the traits of parents and children across the generation
Pedigree
A technique to test for Tay-Sachs Disease in which a narrow tube is inserted into the uteris through the cervix and some of the placenta is removed for testing
Chorionic Villus Sampling (CVS)
Heterozygotes which are phenotypically normal for a disorder, but may transmit the recessive allele to their offspring
Carriers
The most common lethal genetic disease in the United States (caused by a recessive allele)
Cystic Fibrosis
The most common inherited disorder among people of African descent
Sickle-Cell Disease
A degenerative disease of the nervous system caused by a lethal dominant allele that has no obvious phenotypic effect until the affected individual is approximately 35 to 45 years old
Huntington’s Disease
One of the tests done to a fetus to tst for Tay-Sachs Disease, in which a needle is inserted into the uteris and 10mL of amniotic fluid are extracted during the fifteenth week of pregnancy
Amniocentesis
Define the following term:
Character
A heritable feature that varies among individuals
Define the following term:
Trait
Each variant for a character
Define the following term:
True-breeding
Plants who, over many generations of self-pollination, have produced only the same variety of the parental plant
Define the following term:
Hybridization
The mating (or crossing) of two true-breeding varieties for different traits
Define the following term:
P generation or P1 generation
Parental generation
Define the following term:
F1 generation
First filial generation
Define the following term:
F2 generation
Second filial generation
Define the following term:
Alleles
Alternate versions of a gene
Define the following term:
Dominant allele
The allele that controls the phenotype of a heterozygote
Define the following term:
Recessive allele
The allele in a heterozygote with no noticeable phenotypic effects
Define the following term:
Law of Segregation
The two alleles for a heritable character segregate during gamete formation and end up in different gametes
Define the following term:
Punnett Square
A handy diagrammatic device for predicting the allele composition of offspring from a cross between individuals of known genetic makeup
Define the following term:
Homozygote
An organism that has a pair of identical alleles for a gene encoding a character
Define the following term:
Homozygous
Having a pair of identical alleles for a gene encoding a character
Define the following term:
Heterozygote
An organism that has two different alleles for a gene
Define the following term:
Heterozygous
Having two different alleles for a gene
Define the following term:
Phenotype
An organism’s appearance or observable traits
Define the following term:
Genotype
An organism’s genetic makeup
Define the following term:
Testcross
Breeding an organism of unknown genotype with a recessive homozygote
Define the following term:
Monohybrids
All the F1 progeny produced in crosses of true-breeding parents following one trait
Define the following term:
Monohybrid cross
A cross between heterozygotes for one trait
Define the following term:
Dihybrids
The F1 plants produced in a cross between two true-breeding varieties differing for two traits being observed
Define the following term:
Dihybrid cross
A cross between dihybrids
Define the following term:
Law of Independent Assortment
Two or more genes assort independently - that is, each pair of alleles segregates independently of any other pair of alleles - during gamete formation
Define the following term:
Multiplication rule
To determine the probability of multiple events, multiply the probability of one event by the other(s) to see the probability of the total event
Define the following term:
Addition rule
The probability that any one of two or more mutually exclusive events will occur is calculated by adding their individual probabilities
Define the following term:
Pleiotropy
Genes having multiple phenotypic effects
Define the following term:
Quantitative characters
Characters that vary along a continuum
Define the following term:
Complete dominance
Degree of dominance in which one allele completely controls the phenotype of the heterozygote
Define the following term:
Incomplete dominance
In which neither allele shows through in the heterozygote, but a new, intermediate phenotype does
Define the following term:
Codominance
Degree of dominance in which both alleles each affect the phenotype in separate, distinguishable ways
Define the following term:
Tay-Sachs Disease
An inherited disease in humans that expresses incomplete dominance; the brain cells of a homozygote cannot metabolize certain lipids
Define the following term:
Epistasis
The phenotypic expression of a gene at one locus alters that of a gene at a second locus
Define the following term:
Polygenic inheritance
An additive effect of two or more genes on a single phenotypic character
Define the following term:
Multifactorial
Meaning that many factors, both genetic and environmental, collectively influence phenotype
Define the following term:
Pedigree
A family tree describing the traits of parents and children across the generation
Define the following term:
Chorionic Villus Sampling (CVS)
A technique to test for Tay-Sachs Disease in which a narrow tube is inserted into the uteris through the cervix and some of the placenta is removed for testing
Define the following term:
Carriers
Heterozygotes which are phenotypically normal for a disorder, but may transmit the recessive allele to their offspring
Define the following term:
Cystic Fibrosis
The most common lethal genetic disease in the United States (caused by a recessive allele)
Define the following term:
Sickle-Cell Disease
The most common inherited disorder among people of African descent
Define the following term:
Huntington’s Disease
A degenerative disease of the nervous system caused by a lethal dominant allele that has no obvious phenotypic effect until the affected individual is approximately 35 to 45 years old
Define the following term:
Amniocentesis
One of the tests done to a fetus to tst for Tay-Sachs Disease, in which a needle is inserted into the uteris and 10mL of amniotic fluid are extracted during the fifteenth week of pregnancy