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Oral Pathology Test 3 > ch 14 > Flashcards

ch 14 Flashcards

1
Q

What are 4 characteristics of benign bone neoplasms?

A

Asymptomatic:
Slow growing, cortex still there:
Symmetrical:
No metastisis:

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2
Q

What are characteristics of malignant bone neoplasms?

A

Destroys cortex, poorly defined margins, lays down bone outside the cortex.
Everything opposite of Benign neoplasms.

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3
Q

DON’T NEED TO KNOW!!!Osteogenesis imperfecta?

Is it inherited?

A

Defect in Type 1 collagen maturation

Most common inherited disease

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4
Q

DON’T NEED TO KNOW!!!What are symptoms of osteo imperfecta?

A

Bone fragile
Blue sclera
altered teeth (that look like dentinogenesis imperfecta)

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5
Q

DON’T NEED TO KNOW!!!What do osteo imperfecta teeth look like?

A

Blue to brown translucence, pulpal obliteration

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6
Q

Osteopetrosis? What causes it?

A

Increased bone density.

failure of normal osteoclasts

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7
Q

What does Osteopetrosis look like radiographically?

A

Radioopaque, can’t see through it.

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8
Q

Cleidocranial dysplasia?

A

syndrome with dental and clavicle abnormal

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9
Q

What happens with clavicle on cleidocranial dysplasia?

What happens with teeth?

A

small or no clavicle

retained primary teeth, impacted permanent teeth (lots of teeth)

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10
Q

Focal osteoporotic marrow defect?
What gender?
Biopsy needed and why?
Treatment required?

A

benign hematopoetic marrow defect radiolucency with trabeculations.
women.
Yes, only to differentiate between ameloblastoma.
No treatment required.

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11
Q

Idiopathic osteosclerosis?
Does it have a rim?
Which part of the mouth is it common?

A

Focal area of increased radioopacity, unknown cause, cannot be attributed to anything else.
No rim surrounding it.
Mandible.

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12
Q

What’s the difference between condensing osteitis and idiopathic osteosclerosis?

A

Condensing osteitis: associated with infection (carious, large filling)
Idiopathic osteosclerosis: virgin tooth no known causes.

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13
Q

Pagets disease of bone?
Does it affect more than one bone?
Does it cause pain?

A

disease with abnormal resorption and deposition of bone.
Yes more than one bone.
Yes it causes pain.

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14
Q

What are clinical manifestations of pagets?

A

Hat not fitting,
recent spaces between bone
Dentures don’t fit

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15
Q

When will hypercementosis associate with pagets disease?

A

when multiple teeth are involved

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16
Q

What does pagets disease of bone look like radiographically?

A

“cotton wool” appearance of the bone (looks wispy)

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17
Q

What will a pagets disease patient have high levels of?

What levels will be normal?

A

Serum alkaline phosphatase..,

calcium and phosphorus

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18
Q

What is something that pagets disease patients are likely to get?

A

Osteosarcoma

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19
Q

Are central giant cell granulomas neoplasms?

A

No

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20
Q

What is a central giant cell granuloma?

How is it discovered if it’s asympotomatic?

A

Nonneoplastic Anterior jaw midline lesion.

discovered by Xray

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21
Q

What does a central giant cell granuloma look like xray?

What about histology is it similar to?

A

well delineated big hole in the jaw in the midline
noncorticated margins.

Histo: hyperparathyroidism/cherubism

22
Q

What is the treatment for central giant cell granuloma?

A

curettage if small.

corticosteroids if more aggressive

23
Q

What is cherubism?
What does it look like?
When does it occur?
When does it go away?

A

developmental bilateral jaw lesion.
bilateral chubby cheeks, eyes upturned.
ages 2-5
by puberty it regresses.

24
Q 
What is a traumatic bone cyst?
What causes it?
What ages?
Where does it occur?
What does it look like when involving several teeth?
A

benign, empty/fluid filled cavity within bone.
Trauma/hemorrage to bone, not enough healing.
ages 10-20.
In the mandible..
xray SCALLOPING between the roots.

25
Q

What is a misnomer about traumatic bone cyst?

A

the lesion isn’t a real “cyst” because it doesn’t have an epithelial lining

26
Q

What is an Aneurysmal bone cyst?
Is it a true cyst?
What does it look like?
Is it rapid swelling?

A

Intraosseous blood filled spaces with CT.
Not a true cyst, no epi lining.
Blowout or ballooning of bone, blood soaked sponge.
Yes rapid swelling.

27
Q

What are fibro-osseous lesions?

A

normal bone replaced by fibrous tissue.

28
Q

What is fibrous dysplasia?
What causes it?
If it’s polyostotic what syndromes are common?

A

tumorlike condition of normal bone replaced by fibrous CT intermixed with bone.
caused by postzygotic mutation.
Jaffe-Lichtenstein/Mcune-albright syndromes

29
Q

Is monostotic or polyostotic more common in fibrous dysplasia? How much?

A

Mono: 80%

30
Q

What is the radiographic feature of fibrous dysplasia?

A

fine ground glass opacity. (iced glass)

31
Q

What does jaffe-lichtenstein sydrome present as?

And what about mcune albright?

A 
Cafe au lait spots (coast of maine)
polyostotic fibrous dysplasia
MA: (above and also below)
early onset puberty
bony hard swelling
32
Q

What does a focal cemento osseous dysplasia look like?
What type of person gets it?
Where is it found

A

Thin radiolucent rim.
Females, caucasian.
posterior mandible

33
Q

What is periapical cemento-osseous dysplasia?
Why do dentists get sued over this?
What do later stages look like?
Where is it found?

A

lesion involving the periapex of tooth.
It looks like a periapical granuloma that needs a RCT.
Mixed RO-RL lesions.
Anterior mandible.

34
Q

What is florid cemento-osseous dysplasia?

What time of person is it common?

A

Multiple focal involvement not limited to anterior mandible.
mostly african females.

35
Q

What is an ossifying fibroma?
What does it do to roots?
What does it do to mandible cortex?
What does it look like?

A

True neoplasm with growth.
Main ossifying fibroma that causes root divergence.
downward bowing of the inferior cortex of mandible.
mixed RO-RL lesion.

36
Q

What is difference between juvenile ossifying fibroma and ossifying fibroma?

A

JOF: male more than female, Max more than Mand.

37
Q

What’s an osteoma?
Where’s it located?
What syndrome is osteoma associated with?

A

Bony hard mass growing off the head (similar to torus)
Anywhere on the head.
Gardner syndrome

38
Q

What does gardner syndrome present as?

A

Colonic polyps that will become cancer, skeletal abnormalities, dental abnormalities, epidermoid cysts.

39
Q

What are the most risky things to happen because of Gardner syndrome? What’s the second most likely thing to develop?

A

Adenocarcinoma grows from colon polyps..

Osteoma will also develop

40
Q

What are the dental abnormalities of Gardner Syndrome?

A

Supernumerary teeth..

41
Q

Osteoblastoma and Osteoid osteoma?
What does osteoid osteoma do to cause pain?
Which one is largest? size?

A

benign bone tumors.
Produces prostaglandins (give aspirin)
Osteoblastoma (larger than 2cm)

42
Q

Does osteoblastoma produce prostaglandins and pain? and can it be relieved by aspirin?

A

Yes it produces it, but it’s too big to be relieved by aspirin.

43
Q

When is the pain commonly felt with osteoid osteoma? What can it be relieved by ?

A

At night. by aspirin

44
Q

What is the appearance of osteoblastoma and osteoid osteoma?

A

Radiolucent, well defined, may have a RO spot in the middle.

45
Q

What’s a cementoblastoma?
Where does it occur?
What’s it look like xray?
How is it treated?

A

Neoplasm of cementoblasts.
Majority in mandible, molar/pre-molar.
RO mass that covers the root of the tooth.
Removed with the entire tooth.

46
Q

What’s an Osteosarcoma?
What age is common?
Where does it usually occur?
What’s it look like xray?
What’s the trianglular elevation of periosteum called that’s found?
What’s a common thing to happen to the pdl?

A 
Malignancy of mesenchymal origin..
10-20 more common. and after 50
extragnathic (outside the jaw).
xray "sunburst" appearance of spikes. 
Codman's triangle.
PDL gets a lot wider.
47
Q

What is ewings sarcoma? What causes it?

A

malignancy caused by translocation of 11:22 chromosome

48
Q

Where are most metastatic diseases of jaw orginated?

A 
Breast
lung
thyroid
prostate
kidney
49
Q

What is xray character is metastatic jaw malignancy?

A

Moth-eaten, widened PDL.

50
Q

What’s a chondrosarcoma?

A

Malignancy of bone caused by cartilage

Oral Pathology Test 3 (12 decks)

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