ch 13 Flashcards
What is anemia? What can it mean?
decrease in RBC’s.
Renal, Liver, inflammatory, malignancies
What are oral symptoms of anemia?
Glossodynia (pain)
Glossopyrosis (burning)
Tongue atrophy (bald tongue)
What is thrombocytopenia? What can spleen do to cause it? What oral indication can show thrombocytopenia?
decreased amount of blood platelets.
Sequestration in the spleen (splenomegaly).
Petechiae.
DON’T NEED TO KNOW!!!What’s the 2 larger petechiae (in order?)
- purpura
2. Echymosis (biggest)
What are the two types of thrombocytopenia and which one is most serious?
TTP (thrombotic thrombocytopenia purpura)
ITP (idiopathic TP)
TTP is most dangerous
What is lymphoid hyperplasia?
When is it worrisome?
What does it look like?
tonsillar region gets bigger.
It’s worrisome if it’s asymetrical.
little papules that occur in the mouth
What is leukemia?
malignancy of hematopoietic stem cells
What are the 4 leukemias to know?
- Acute myeloid leukemia
- Chronic myeloid leukemia
- Acute lymphoblastic leukemia
- Chronic lymphoblastic leukemia
Which leukemia is common type in children vs adult?
Child: ALL
Adult: CLL
What’s the chromosome that affects Chronic Myeloid Leukemia?
Philadelphia chromosome
How does leukemia present in the mouth? Color? Firmness?
Gingival hyperplasia, pigmented, soft (boggy)
What is langerhans cell histiocytosis?
What age?
What does it look like radiographically?
What can test for histologically to diagnose it?
cancer of langerhans cells.
Less than 15 years.
Punched out bone.
Electron Microscopy for Birbeck granules.
What is hodgkins lymphoma?
What are the neoplastic cells call?
Where do most of the lymph nodes for this occur?
Malignancy of lymph
Reed-Sternberg cells
Neck
DON’T NEED TO KNOW!!!What’s the most common lymphoma in the mouth? (diffuse large B cell)
Non-hodgkins lymphoma (DLBCL)
DON’T NEED TO KNOW!!!What is lymphoma AKA?
Non-hodgkins lymphoma
DON’T NEED TO KNOW!!!What does Non hodgkins lymphoma appear like in the mouth?
Purple-red, non-tender, BOGGY swellings.
DON’T NEED TO KNOW!!!What is mycosis fungoides?
What is the aggressive spreading on the skin called and how long till dead? What does it look like?
Cutaneous T-cell lymphoma that resembles a fungal infection
Sezary syndrome 3 years. splotches and swellings on the skin (SS)
DON’T NEED TO KNOW!!!What is the intraepithelial aggregate called on mycosis fungoides? (histology)
What’s the thing called that makes it likely to invade the epidermis?
Pautriers microabcesses
Epidermotropism
DON'T NEED TO KNOW!!!What is Burkitts lymphoma? Where's it found? How common from EBV? What's the average age? What's histology look like?
Bcell malignancy (radiolucency) Jaw 90% from EBV 7 years old. Starry sky pattern
DON’T NEED TO KNOW!!!What’s another name for NK/T cell lymphoma?
angiocentric Tcell lymphoma
DON’T NEED TO KNOW!!!What happens to the palate with NKTcell lymphoma?
destruction of the midline (big hole)
DON’T NEED TO KNOW!!!What age group gets NKT cell lymphoma?
adults
What is a multiple myeloma?
What does it present as?
malignancy of plasma cell origin.
Many punched out radiolucencies of bone.
What’s the most common hematologic malignancy of africans?
Multiple myeloma
What is the most common malignancy of the bone?
2nd most common?
Metastatic disease.
Multiple myeloma.
What are the proteins called that are found in multiple myeloma?
What’s radiograph presentation?
What are the meds given?
Bence Jones proteins
Punched out border
Bisphosphonates
