ch 13

Question 1

What is anemia? What can it mean?

Answer 1

decrease in RBC’s.

Renal, Liver, inflammatory, malignancies

Question 2

What are oral symptoms of anemia?

Answer 2

Glossodynia (pain)
Glossopyrosis (burning)
Tongue atrophy (bald tongue)

Question 3

What is thrombocytopenia? What can spleen do to cause it? What oral indication can show thrombocytopenia?

Answer 3

decreased amount of blood platelets.
Sequestration in the spleen (splenomegaly).
Petechiae.

Question 4

DON’T NEED TO KNOW!!!What’s the 2 larger petechiae (in order?)

Answer 4

1. purpura

2. Echymosis (biggest)

Question 5

What are the two types of thrombocytopenia and which one is most serious?

Answer 5

TTP (thrombotic thrombocytopenia purpura)
ITP (idiopathic TP)
TTP is most dangerous

Question 6

What is lymphoid hyperplasia?
When is it worrisome?
What does it look like?

Answer 6

tonsillar region gets bigger.
It’s worrisome if it’s asymetrical.
little papules that occur in the mouth

Question 7

What is leukemia?

Answer 7

malignancy of hematopoietic stem cells

Question 8

What are the 4 leukemias to know?

Answer 8

1. Acute myeloid leukemia
2. Chronic myeloid leukemia
3. Acute lymphoblastic leukemia
4. Chronic lymphoblastic leukemia

Question 9

Which leukemia is common type in children vs adult?

Answer 9

Child: ALL
Adult: CLL

Question 10

What’s the chromosome that affects Chronic Myeloid Leukemia?

Answer 10

Philadelphia chromosome

Question 11

How does leukemia present in the mouth? Color? Firmness?

Answer 11

Gingival hyperplasia, pigmented, soft (boggy)

Question 12

What is langerhans cell histiocytosis?
What age?
What does it look like radiographically?
What can test for histologically to diagnose it?

Answer 12

cancer of langerhans cells.
Less than 15 years.
Punched out bone.
Electron Microscopy for Birbeck granules.

Question 13

What is hodgkins lymphoma?
What are the neoplastic cells call?
Where do most of the lymph nodes for this occur?

Answer 13

Malignancy of lymph
Reed-Sternberg cells
Neck

Question 14

DON’T NEED TO KNOW!!!What’s the most common lymphoma in the mouth? (diffuse large B cell)

Answer 14

Non-hodgkins lymphoma (DLBCL)

Question 15

DON’T NEED TO KNOW!!!What is lymphoma AKA?

Answer 15

Non-hodgkins lymphoma

Question 16

DON’T NEED TO KNOW!!!What does Non hodgkins lymphoma appear like in the mouth?

Answer 16

Purple-red, non-tender, BOGGY swellings.

Question 17

DON’T NEED TO KNOW!!!What is mycosis fungoides?

What is the aggressive spreading on the skin called and how long till dead? What does it look like?

Answer 17

Cutaneous T-cell lymphoma that resembles a fungal infection

Sezary syndrome 3 years. splotches and swellings on the skin (SS)

Question 18

DON’T NEED TO KNOW!!!What is the intraepithelial aggregate called on mycosis fungoides? (histology)
What’s the thing called that makes it likely to invade the epidermis?

Answer 18

Pautriers microabcesses

Epidermotropism

Question 19

DON'T NEED TO KNOW!!!What is Burkitts lymphoma?
Where's it found?
How common from EBV?
What's the average age?
What's histology look like?

Answer 19

Bcell malignancy (radiolucency)
Jaw
90% from EBV
7 years old. 
Starry sky pattern

Question 20

DON’T NEED TO KNOW!!!What’s another name for NK/T cell lymphoma?

Answer 20

angiocentric Tcell lymphoma

Question 21

DON’T NEED TO KNOW!!!What happens to the palate with NKTcell lymphoma?

Answer 21

destruction of the midline (big hole)

Question 22

DON’T NEED TO KNOW!!!What age group gets NKT cell lymphoma?

Answer 22

adults

Question 23

What is a multiple myeloma?

What does it present as?

Answer 23

malignancy of plasma cell origin.

Many punched out radiolucencies of bone.

Question 24

What’s the most common hematologic malignancy of africans?

Answer 24

Multiple myeloma

Question 25

What is the most common malignancy of the bone?

2nd most common?

Answer 25

Metastatic disease.

Multiple myeloma.

Question 26

What are the proteins called that are found in multiple myeloma?
What’s radiograph presentation?
What are the meds given?

Answer 26

Bence Jones proteins
Punched out border
Bisphosphonates