Ch. 11 - Somatosensation (FINAL) Flashcards
neuromuscular junctions: motor neurons layer
layer 4 CARRIES effector message to muscles
- high ACh: depolarization of muscle cells
spinal cord: sections
- cervical
- head, neck, arms, hands.
- C1/C2 sever: quadraplegia - thoracic (torso)
- lumbar (hips and legs)
- sacral (legs and feet)
- coccygeal (tailbone)
corticospinal tracts (2)
lateral: right side
anterior: body midline
forebrain: basal ganglia and syndromes
LASHEY, 1950s.
force of movement
deep in white matter
made up of the striatum and globus pallidus
hyperkinetic syndrome: excessive/unwanted movement or dyskenesia
hypokinetic syndrome: insufficient movement or bradykinesia
motor sequence : 3 steps
- prefrontal cortex (what goal to select… grab? poke?)
- pre-motor cortex
- primary motor cortex/M1 (executes skilled movement)
cerebellum: motor coordination
purkinje cells in hindbrain
timing and accuracy of movement
has correctional power over actions
brainstem: motor organization
adaptive movements
species-typical (all members of a species have it)
M1 organization (scientists)
Fritsch and Hitzig, 1870s
- discovery: M1 is contralateral
- performed neocortex stimulation of dogs on opposite sides
Penfield, 1930s
- discovery: homunculus and electrical mapping
- confirmed significance of M1 through electrical stimulation
- Graziano, 2009: same experiment but longer stimulation period
Nudo et al., 1996
- discovery: effectiveness of constraint induced therapy
voluntary motor output: pathway
- M1 layer 5
- a) lateral corticospinal tract: contralateral
- b) anterior horn on lateral neuron
- c) limbs and digit control
- a) anterior corticospinal tract: ipsilateral
- b) anterior horn on medial neurons
- c) trunk control
somatosensation: skin types
hairy skin: dendrites are wrapped around hair follicles
glabrous skin: smooth, highly sensitive
somatosensation: receptor types
nociception: irritation or damage, ligand gated channels to communicate chemical message, pain/itch/temperature
hapsis: pressure, touch, mechanical ion channels
propriception: muscle and joint movement, spatial awareness of body, location of limbs
transduction (action potentials) somatosensory pathway
- stimulus
** depolarization - posterior root ganglion
** action potentials - neurotransmitters at synapse
- medulla
- thalamus
- S1
vestibular system (ears)
semicircular canals: head rotation
otolith organs: tilt and gravitational orientation
- utricle and saccule
semicircular canals
anterior duct: nodding
lateral duct: head shake
posterior duct: head tilt