Ch. 11 Environmental/Toxicology Flashcards

1
Q

What component of the brain controls thermoregulation? And through what two processes?

A

Hypothalamus. And via heat conservation and production.

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2
Q

In what two systems are the effects of hypothermia significant?

A

cardiovascular and CNS

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3
Q

What are four effects that hypothermia can have on the cardiovascular system?

A

1) bradycardia;
2) decrease in MAP & CO;
3) Osborne (J) waves
4) Atrial/Ventricular arrhythmias (asystole&V-fib)

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4
Q

What are four effects that hypothermia can have on the CNS system?

A

1) decreasing metabolism
2) <33 C -abnormal electrical activity
3) 19-20 C -EEG may show brain death
4) issues after rewarming has started

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5
Q

Mild hypothermia range and symptoms (7)

A

32-35 C
vigorous shivering, altered judgment, dysarthria, increased respiratory rate, ataxia/apathy as temp decreases, tachypnea/tachycardia, cold diuresis

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6
Q

Moderate hypothermia range and symptoms (7)

A

28-32 C
O2 consumption decreases. further CNS depression, stupor may occur, loss of shivering, arrhythmia risk increases, bradycardia worsens (CO reduces), dilation of pupils

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7
Q

Severe hypothermia range and symptoms (7)

A

<28 C
susceptible to V-fib, further decrease in myocardial contractility, comatose, pulmonary edema, oliguria, hypotension, descreased/absent activity on EEG

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8
Q

Four methods of heat transfer are…

A

conduction, convection, radiation, evaporation

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9
Q

Converting liquid to gas for heat transfer

A

evaporation

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10
Q

heat transfer by electromagnetic waves

A

radiation

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11
Q

heat transferred through air and water vapor molecules around the body

A

convection

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12
Q

direct physical contact transferring heat from warmer object to cooler object

A

conduction

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13
Q

Malignant Hyperthermia pathophysiology

A

Calcium is released into muscle fibers causing sustained contraction due to the rapid depolarization

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14
Q

Malignant Hyperthermia causes: (3)

A

muscle rigidity, excessive heat production, hypermetabolic state increasing temp

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15
Q

What sort of medication causes Malignant Hyperthermia?

A

Succinylcholine

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16
Q

What two issues could Malignant Hyperthermia present in regards to airway?

A

It may prevent mouth opening and limit airway control

17
Q

Malignant Hyperthermia Signs/symptoms: (8)

A
trismus
increased ETCO2
tachycardia
hypertension
mixed acidosis 
rhabdomyolysis
hyperthermia 
truncal or extremity rigidity