Ch. 11 Environmental/Toxicology Flashcards
What component of the brain controls thermoregulation? And through what two processes?
Hypothalamus. And via heat conservation and production.
In what two systems are the effects of hypothermia significant?
cardiovascular and CNS
What are four effects that hypothermia can have on the cardiovascular system?
1) bradycardia;
2) decrease in MAP & CO;
3) Osborne (J) waves
4) Atrial/Ventricular arrhythmias (asystole&V-fib)
What are four effects that hypothermia can have on the CNS system?
1) decreasing metabolism
2) <33 C -abnormal electrical activity
3) 19-20 C -EEG may show brain death
4) issues after rewarming has started
Mild hypothermia range and symptoms (7)
32-35 C
vigorous shivering, altered judgment, dysarthria, increased respiratory rate, ataxia/apathy as temp decreases, tachypnea/tachycardia, cold diuresis
Moderate hypothermia range and symptoms (7)
28-32 C
O2 consumption decreases. further CNS depression, stupor may occur, loss of shivering, arrhythmia risk increases, bradycardia worsens (CO reduces), dilation of pupils
Severe hypothermia range and symptoms (7)
<28 C
susceptible to V-fib, further decrease in myocardial contractility, comatose, pulmonary edema, oliguria, hypotension, descreased/absent activity on EEG
Four methods of heat transfer are…
conduction, convection, radiation, evaporation
Converting liquid to gas for heat transfer
evaporation
heat transfer by electromagnetic waves
radiation
heat transferred through air and water vapor molecules around the body
convection
direct physical contact transferring heat from warmer object to cooler object
conduction
Malignant Hyperthermia pathophysiology
Calcium is released into muscle fibers causing sustained contraction due to the rapid depolarization
Malignant Hyperthermia causes: (3)
muscle rigidity, excessive heat production, hypermetabolic state increasing temp
What sort of medication causes Malignant Hyperthermia?
Succinylcholine