Acid-Base Interpretation Flashcards

1
Q

pH

A

7.35-7.45

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2
Q

PaCO2

A

35-45mmHg

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3
Q

HCO3-

A

22-26

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4
Q

bicarbonate

A

22-26

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5
Q

PaO2

A

80-100

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6
Q

normal values of partial pressure of Oxygen in the blood

A

80-100

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7
Q

normal values of partial pressure of carbon dioxide in the blood

A

35-45mmHg

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8
Q

BE

A

-2/+2

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9
Q

For every 10mmHg change in CO2, how will the pH be affected?

A

the pH will change .08 in the opposite direction

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10
Q

For every 10mEq change in HCO3-, how will the pH be affected?

A

the pH will change .15 in the same direction

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11
Q

For every change in pH of .10, how will the K+ be affected?

A

The K+ will change by .6 in the opposite direction

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12
Q

Formula for bicarb replacement

A

.1 x weight (kg) x base deficit = mEq bicarb needed

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13
Q

Tx for metabolic alkalosis

A

reduce GI suctioning, treat with K+, Mg2+, Na+, Ca2+, Acetazolamide 500mg IV

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14
Q

What does Base Excess represent?

A

Negative number represents deficit of base, positive number is excess of base

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15
Q

BE is accounted for by….

A

Strong and weak acids

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16
Q

When accounting for BE, what is normal difference between Na+ and Cl-?

A

38

17
Q

Anion Gap is filled by what 8 factors?

A

Lactate, Ketones, Toxic Alcohols, ethylene glycol, methanol, propylene glycol, lithium, mannitol

18
Q

Anion Gap is measurement between what and what?

A

Cations and Anions

19
Q

What is the formula and normal range for the uncorrected anion gap?

A

[Na - (Cl + HCO3)] 9-12

20
Q

How do you most accurately calculate the anion gap? What is the normal range?

A

[Na - (Cl + HCO3) + K+] 16-20

21
Q

The following values would indicate respiratory failure and the need to intubate the patient:

A

pH 7.2, CO2 >55, PaO2 <60

22
Q

Why is acidosis more common than alkalosis?

A

Because several acids are generated by normal cellular activities. (684)

23
Q

What is the relationship between the partial pressure of CO2 and pH?

A

More PCO2, lower pH. They are inversely related. (684)

24
Q

What happens to the hydrogen ions and bicarbonate ions when the concentration of carbon dioxide rises? What happens to the pH?

A

When carbon dioxide rises, additional hydrogen ions and bicarbonate ions are released and the pH goes down. (684)

25
Q

The organic/metabolic acid that is created from the anaerobic metabolism of pyruvic acid is…

A

lactic acid (684)

26
Q

The organic/metabolic acid that is created from the breakdown of fatty acids is….

A

ketones (684)

27
Q

What is a buffer system defined as?

A

weak acid and its dissociation products: a hydrogen ion and an anion. (685)

28
Q

How does the rise of PCO2 affect the smooth muscles in the walls of arterioles in the area?

A

The rise of PCO2 causes the smooth muscles to relax which causes increased blood flow. (573)

29
Q

How is airflow directed to the lobules in which the PCO2 is high?

A

When PCO2 increases, the bronchioles dilate and when the PCO2 decreases, the bronchioles will constrict. (573)

30
Q

When the PO2 is low, the precapillary sphincters in the alveolar capillary beds constrict which causes increased blood flow to what section of the capillary bed?

A

The pulmonary lobules in which the PO2 are relatively high. (573)