Ch. 10 Flashcards
bacteria divide via
binary fission
_____,_______ bacterial chromosome is replicated
single, circular
begins at ____, and goes in a _________ fashion until end
origin, bidirectional
_______ forms to divide the cell into 2
septum
uncondensed chromosome/DNA
chromation
radial loops held in place by
scaffold proteins
DNA wrapped around histone proteins
Nucleosome
portion of genome not expressed
heterochromatin
portion that is expressed
euchromatin
___ pairs of chromosomes
23
diploid number
46
X-shaped chromosome connected by
centromere
replicated chromosomes are connected by
kinetochores
5 phases of cell cycle
G1
S
G2
Mitosis
Cytokinesis
5 phases of mitosis
prophase
prometaphase
metaphase
anaphase
telophase
G1
primary growth phase, longest phase
S
responsible for the synthesis or replication of DNA
G2
second growth phase, replication of organelles, assembly of microtubules at spindle, chromosomes undergo condensation
prophase
chromosomes condense, centrioles move to poles, spindle apparatus assembled,
nuclear envelop dissolve
prometaphase
spindle apparatus attaches to kinetochores,
2nd set of microtubules form attach to kinetochores,
microtubules begin to pull chromosomes to center
metaphase
microtubules align chromosomes at center,
imaginary plane; center of cell where chromosomes align
metaphase plate
anaphase
removal of cohesion proteins causing centromeres to separate
microtubules pull sister chromatids towards poles
telophase
spindle apparatus disassembles
nuclear envelope forms around each set of sister chromatids
chromosomes begin to uncoil
nucleolus reappears in each new nucleus
cytokinesis
animal cells: constriction of actin filaments produces cleavage furrow
plant cells: plasma membrane forms a cell plate between nucleus
three checkpoints
G1/S
G2/M
late metaphase
G1/S checkpoint
cell decides to divide, if doesn’t pass goes to G0
G2/M
checks DNA replication otherwise back to S
Late metaphase
all chromosomes are attached to spindle and everything is in place, if not stays in metaphase or goes back to prophase
genes that disturb the cell cycle when they are mutated
tumor-suppressor
proto-oncogenes