Ch. 1-4 Flashcards

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1
Q

What is every living thing made up of basic elements?

A

carbon, oxygen, hydrogen, and nitrogen

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2
Q

What molecules do the basic elements of carbon, oxygen, hydrogen, and nitrogen form?

A

sugars, amino acids, fatty acids, and nucleotides

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3
Q

What macromolecules do the molecules of sugars, amino acids, fatty acids, and nucleotides combine into?

A

polysaccharides (complex carbohydrates), proteins, fats, and nucleic acids

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4
Q

What is the definition of Metabolism?

A

Metabolism is the transfer of energy from one form to another: for example, our muscles converting ATP into movement

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5
Q

Explain the negative feedback mechanism

A

Negative feedback mechanism consists of receptor that detects stimulus and sends it to the integrating centre which sends the signal to the effector and then response

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6
Q

Explain the positive feedback mechanism

A

Childbirth would be the example for positive feedback mechanism where the response is increasing the original stimulus until the baby is born

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7
Q

Is it healthy adult male or adult female that has more percentage of water?

A

It is healthy adult male that has more percentage of water in their body, female usually has more fat

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8
Q

What molecules are hydrophilic?

A

Polar molecules

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9
Q

What molecules are hydrophobic?

A

Non-polar molecules

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10
Q

What is amphipathic?

A

Molecules that are both hydrophilic and hydrophobic

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11
Q

What atom does all living thin is based on?

A

Carbon

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12
Q

What are building molecules of the body?

A

Macromolecules

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13
Q

What componenets are macromolecules are assembled from?

A

Monomers

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14
Q

What is polymer?

A

Assembled chain of monomers

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15
Q

How is covalent bond formed?

A

By removing hydroxyl group (OH) from one subunit and Hydrogen from another subunit

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16
Q

What is dehydration synthesis

A

process of linking together two subunits to form a polymer, removal of a molecule of water (H2O)

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17
Q

What is hydrolysis?

A

process of disassembling polymers into component monomers which is the reverse of dehydration synthesis, molecule of water is added to break the covalent bond between the monomers

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18
Q

What are protein made up of?

A

amino acids

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19
Q

What is peptide bond?

A

The covalent bond linking two amino acids together

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20
Q

What is polypeptide?

A

The assembled polymer

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21
Q

What are amino acids?

A

small molecules with a simple basic structure

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22
Q

What are 3 groups of a carbon atom is attached to form the amino acids?

A

an amino group (-NH2)
a carboxyl group (-COOH)
a functional group (R)

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23
Q

What number of amino acids is essential from total 20 amino acids and what are they?

A

9 are essential which are histidine, isoleucine, leucine, lysine, methionine, phenylalanine,
threonine, tryptophan, and valine and you get it from diet

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24
Q

What are 4 levels of protein structure and explain the characteristic of each protein structure levels.

A
  1. Primary-Linear chain of amino acids
  2. Secondary-Sheet shaped and alpha helix of amino acids
  3. Tertiary-3 Dimensional folding pattern of protein
  4. Quaternary-Same 3 dimensional fold pattern but has one more of it
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25
Q

What causes protein unfold or denature?

A

Changes to the environment of the protein

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26
Q

What environment affects hydrogen bonding or hydrophobic interactions?

A

Increased temperature or lower pH

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27
Q

Is denature protein active or inactive?

A

Inactive

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28
Q

Does denaturing proteins impact amino acids?

A

No

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29
Q

What is anabolic reaction?

A

Enzymatic reactions that build molecules

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30
Q

What is catabolic reaction?

A

Enzymatic reactions that break down molecules

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31
Q

What are enzymes?

A

biological catalyst and is almost always a protein, it speeds up the rate of a specific chemical reaction in the cell

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32
Q

What do DNA and RNA have in common?

A

They have monomers called nucleotides

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33
Q

What are 3 parts that nucleotide has?

A
  1. Five-carbon sugar (ribose or deoxyribose)
  2. Phosphate
  3. Nitrogenous base
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34
Q

What does Adenine (A) pair with and Cytosine (C) pair with in structure of DNA?

A

Adenine (A) pairs with Thymine (T)
Cytosine (C) pairs with Guanine (G)

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35
Q

What does Adenine (A) pair with in structure of RNA?

A

Adenine (A) pairs with Uracil (U) in RNA

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36
Q

What does carbonhydrates do?

A

Carbohydrates make up the structural framework of cells and play a critical role in energy production and storage

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37
Q

What ratio does carbonhydrate contain elements C, H, O?

A

a 1:2:1 ratio

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38
Q

What are simple carbonhydrates made up of?

A

Simple carbohydrates are made up of one or two monomers

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39
Q

What are complex carbonhydrates made up of?

A

Complex carbohydrates are made up of polymers

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40
Q

What do monosaccharides consist of?

A

Monosaccharides consist of only one monomer subunit, such as sugar glucose (C6H12O6)

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41
Q

What do disaccharides consist of?

A

Disaccharides consist of two monosaccharides, such as sugar sucrose which contain two monosaccharides: glucose and fructose

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42
Q

What does surcrose have?

A

glucose and fructose (table sugar)

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43
Q

What does Lactose have?

A

glucose and galactose (milk)

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44
Q

What does Maltose have?

A

glucose and glucose (grain)

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45
Q

Is fibre digested in our digestive tract?

A

Fibre is a complex carbohydrate that is not digested in our digestive tract

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46
Q

What subunits do fats have?

A
  1. Fatty acids
  2. Glycerol
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47
Q

What is hydrocarbon for fatty acids?

A

Chains of C and H atoms

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48
Q

What group does hydrocarbon has at the end to from fat molecule?

A

The chain ends with a carboxyl (-COOH) group

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49
Q

What are examples of saturated fats and unsaturated fats?

A

Saturated fats:Meat, poultry, dairy, eggs, coconut oil, palm oil, butter, avocados
Unsaturated fats:Olive oil, fish, peanut oil (healthy)& Corn oil, vegetable oil, canola oil, safflower oil (highly processed refined oils are considered less healthy)

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50
Q

How are transfats created and what is that process called?

A

Trans fats are created by heating liquid vegetable oils in the presence of hydrogen gas, a process called hydrogenation

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51
Q

Where is cholesterol synthesized and located?

A

Cholesterol is synthesized by liver and they are found in liver and brain cells

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52
Q

What are functions of cholesterol?

A
  1. Maintain cell membrane flexibility
  2. Produce steroid hormones
  3. Produce bile (used to break down fats)
  4. Help transport fats through bloodstream (HDLs and LDLs)
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53
Q

What are phospholipids?

A

primary fats found in cell membranes, along with some cholesterol and they are amphipathic

54
Q

What does plasma membrane of the cell?

A

forms the boundary of the cell

55
Q

What is cytoplasm?

A

Cytoplasm fills the interior of the cell and includes the organelles

56
Q

What is cytosol?

A

Cytosol is the fluid component of the cytoplasm

57
Q

What does receptor of membrane do?

A

Receptors bind to substances outside of the cell and affect the function of that cell, such as hormones

58
Q

What are antigen of membrane?

A

Antigens are membrane proteins that act as markers, such as bloodtype proteins

59
Q

What does transport of membrane do?

A

Transport allows substances to cross the membrane, such as ion channels or carrier proteins

60
Q

What does adhension of membrane do?

A

Adhesion connects cells together

61
Q

What does gap junctions of membrane do?

A

Gap junctions allow cells to directly communicate

62
Q

What structures do prokaryotic cells have in common?

A

Nucleoid region, cytoplasm, cell membrane, cell wall(gram positive/negative), capsule

63
Q

What structure do prokaryotic cells sometimes have?

A

Flagellum (plural, flagella): protein fibre that extends from the cell surface, Pilus (plural, pili): like a short flagellum which exchange information between cells

64
Q

What structures do eukaryotic cells have in common?

A

Plasma membrane, cytoplasm, and nucleus

65
Q

What structure do eukaryotic cells sometimes have?

A

Cell wall for fungi some protists, and plants

66
Q

What is nuclear membrane?

A

a doublemembrane, also called nuclear envelope

67
Q

What does Nuclear pores do?

A

allow molecules to move into and out of nucleus

68
Q

What is Nucleolus?

A

Nucleolus is site of transcription of ribosomal RNA

69
Q

What does rough ER do?

A

contains ribosomes and is site of protein synthesis (translation)

70
Q

What is smooth ER ?

A

the site of lipid and carbohydrate synthesis

71
Q

What are golgi bodies?

A

flattened membranes that collect, modify, package, and distribute molecules manufactured in the cell

72
Q

What does mitochondria do?

A

Mitochondria produce energy in form of ATP through process of oxidative phosphorylation containing DNA and ribosome

73
Q

What is ribosome composed of and what does it do?

A

composed of ribosomal RNA (rRNA) and protein
Does protein synthesis

74
Q

What are lysosomes?

A

Lysosomes contain digestive enzymes that break down macromolecules and old organelles

75
Q

What are Peroxisomes?

A

Peroxisomes break down long-chain fatty acids for use by mitochondria to produce ATP and contain molecules that help to detoxify substances
Liver cells contain high amounts of peroxisomes

76
Q

What are centrioles?

A

Centrioles, found in most eukaryotic cells except for plants and fungi, are involved in the organization of spindle fibres (microtubules) that transport chromosomes during cell division

77
Q

What are microtubules?

A

Microtubules: large (25nm) hollow tubes

78
Q

What are Intermediate filaments?

A

10 nm in width, intertwined rope structure

79
Q

What are Microfilaments?

A

7 nm in width, composed of actin proteins

80
Q

What does collagen do?

A

gives tissues strength and resists stretching, such as skin, bones, and tendon

81
Q

What does elastin do?

A

gives tissues flexibility, such as skin, bladder, lungs, and blood vessels

82
Q

What are Integrins?

A

Integrins are membrane-spanning proteins that help to transfer signals to the inside of the cell

83
Q

What does Fibronectin do?

A

Fibronectin connects integrins to other extracellular proteins

84
Q

What are Proteoglycans?

A

Proteoglycans are glycoproteins that hold water and allow tissues to be highly hydrated, such as skin and joints

85
Q

What are tight junction?

A

Tight junctions hold some cell types together and prevent molecules from moving between cells, such as the blood-brain barrier

86
Q

What are Adhering junctions?

A

Adhering junctions anchor cells to the ECM, found in cells that undergo a lot of stretching, such as skin

87
Q

What are gap junctions?

A

Gap junctions form channels that directly connect cells together and allow them to communicate, such as in the heart muscle to allow for simultaneous contraction

88
Q

What is simple diffusion?

A

Simple diffusion is when molecules move from an area of higher concentration to an area of lower concentration
No ATP and membrane protein required

89
Q

What is osmosis?

A

Osmosis is when water moves from an area of higher water concentration to an area of lower water concentration—no ATP required

90
Q

What happens if solution is hypertonic?

A

Water will move from cell into solution; cell will shrink

91
Q

What happens if solution is hypotonic?

A

Water will move from solution into cell; cell will swell and could burst

92
Q

What happens if solution is isotonic?

A

Water will move equally into and out of cell; cell will stay the same

93
Q

What is facilitated diffusion?

A

Requires membrane protein, no ATP, and molecules move down their concentration gradient as channels allow for it

94
Q

What is primary active transport?

A

Requires membrane protein carriers, ATP required, and molecules move against their concentration gradient

95
Q

What is sodium and potassium pump?

A

One of membrane protein carriers that use ATP to pump 3 Na+ out of the cell and 2 k+ into the cell

96
Q

What is proton pump?

A

One of membrane protein carriers that uses energy to pump protons across a membrane

97
Q

What is chemiosmosis?

A

formation of adenosine triphosphate (ATP) by the movement of hydrogen ions (H+) across a membrane

98
Q

What are symport and antiport?

A

Symport:substances move in the same direction
Antiport:substances move in opposite directions

99
Q

What does secondary active transport do?

A

Secondary active transport involves the use of the sodium gradient outside of cells to pull other nutrients such as glucose or amino acids into a cell so that ATP is not required

100
Q

What is endocytosis?

A

Endocytosis is the engulfing of substances outside of the cell in order to form a vesicle that is brought inside the cell

101
Q

What are phagocytosis and pinocytosis of endocytosis?

A

Phagocytosis: solids, such as immune cell engulfing pathogens
Pinocytosis: fluids, such as human egg engulfing fluids with nutrients before fertilization

102
Q

What is exocytosis?

A

Exocytosis is the discharge of substances from vesicles at the inner surface of the cell

103
Q

What bond ca energy be released?

A

Energy can be released from molecules that have C–H bonds

104
Q

What does aerobic respiration require?

A

The process of aerobic respiration requires oxygen and glucose to make ATP

105
Q

What is oxidation of cellular respiration?

A

Oxidation is the loss of electrons

106
Q

What is reduction of cellular respiration?

A

Reduction is the gain of electron

107
Q

What are two stages of cellular respiration?

A

Glycosis and Krebs cycle

108
Q

Where does glycosis occur and does it need oxygen?

A

Occurs in the cytoplasm
Does not require oxygen to generate ATP

109
Q

Where does Krebs cycle occur and what is the process of it?

A

Occurs in mitochondria
Harvests energy-rich electrons and protons (NADH) through a cycle of oxidation reactions
Electrons passed to an electron transport chain to power the production of ATP

110
Q

What is glycosis?

A

Glycolysis is a sequence of chemical reactions that break one glucose molecule (six carbons) into two pyruvate molecules (three carbons)

111
Q

What is substrate level phosphorylation?

A

The breaking of bonds is used to form ATP

112
Q

What is phosphorylation?

A

Phosphorylation is the process of adding a phosphate to ADP

113
Q

How many ATP does glycosis produce?

A

Glycosis yields small amount of ATP, only four ATP are made for each molecule of glucose

114
Q

What is oxidation of pyruvate?

A

In the presence of oxygen, the first step of oxidative respiration in the mitochondrion

115
Q

What does pyruvate dehydrogenase do?

A

They cleave off one of three carbons from pyruvate when it’s being oxidized

116
Q

How is acetyl-CoA is formed during pyruvate oxidation?

A

Carbon leaves as CO2, h leaves and adds to the NAD to form NADH, remaining two carbons join CoA to form acetyl-CoA

117
Q

What happens to plenty of ATP during oxidation?

A

The plenty of ATP causing acetyl-CoA lead to the fat synthesis

118
Q

Explain 3 stages for Krebs Cycle

A
  1. Acetyl-CoA enters the cycle and binds to a four-carbon molecule, forming a six-carbon molecule.
  2. Two carbons are removed as CO2 and their electrons donated to NAD+. In addition, an ATP is produced.
  3. The four-carbon molecule is recycled, and more electrons are extracted, forming NADH and FADH2.
119
Q

What does mitochondria use to make ATP?

A

Chemiosmosis

120
Q

What does proton pump use to pump protons across the cristae?

A

Proton pumps use energetic electrons extracted from food molecules to pump protons across the cristae

121
Q

Where do NADH and FADH2 transfer their electrons?

A

Electron transport chain

122
Q

What is electron transport chain and what does it do?

A

It is a series of membraneassociated molecules and they transport electrons to each other and act as proton pumps

123
Q

What are the macromolecules that can be broken down into ATP?

A

All of them including
Polysaccharides: glucose
Protein: amino acids
Triglycerides: fatty acids and glycerol
Nucleic acids: nucleotides

124
Q

Where do organisms rely on to produce ATP if there is no oxygen?

A

They rely on the glycosis

125
Q

What happens during the process of fermentation?

A

the hydrogen atoms from the NADH generated by glycolysis are donated to organic molecules, and NAD+ is regenerated

126
Q

What does getting continual NAD+ allow for?

A

Continual of Glycosis

127
Q

What does fermentation in yeast produce?

A

NAD+ and ethanol

128
Q

What does fermentation in animals produce?

A

NAD+ and lactate (lactic acid)

129
Q

How is ATP produced from muscle and liver cells?

A

ATP is produced from burning fats in muscle and liver

130
Q

What are the hormones that stimulate breaking fat into ATP or maintain blood sugar?

A

Glucagon
Epinephrine and norepinephrine
Growth Hormone
DHEA
Thyroid hormones