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Pharmaceutics 1 > Ceutics 4 Test 1 > Flashcards

Ceutics 4 Test 1 Flashcards

1
Q

Impact of Particle Size

A 
Dissolution Rate
Suspendability of Suspensions
Uniformity of Dose
Penetrability of particles for inhalation
Lack of grittiness for dermatologicals
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2
Q

Sieve Analysis

A

Particles passed through series of sieves, proportions determined

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3
Q

Andersen Cascade Impactor

A

Particle size determination for inhalation

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4
Q

What impacts particle flow?

A

Size, Shape, Porosity

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5
Q

What is Tapped and Bulk density for?

A

Determine flow and compressibility, determine storage needs

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6
Q

Pulverization

A

Comminution using a solvent that can be easily removed

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7
Q

Levigation

A

Trituration while moistened with a liquid that powder is insoluble in

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8
Q

Factors of Blending

A

Size
Shape
Density
Electrostatic Forces

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9
Q

Dentifrices

A

for teeth

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10
Q

Insufflations

A

for body cavities

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11
Q

Hygroscopic

A

absorbs moisture from air

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12
Q

Deliquescent

A

absorbs moisture from air to extent they liquefy

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13
Q

Efflorescent

A

Liberates water of hydration when relative humidity is low

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14
Q

Eutectic

A

mixture with melting point less than room temp, liquefy when in close prolonged contact

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15
Q

Efferescent

A

Acid base reaction, makes CO2

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16
Q

Advantages of Capsules

A 
Masks tastes/appearnce
Identifiable
Flexible
Easy to swallow
Uniformity
Easy to mass produce
Stable
17
Q

Disadvantages of Capsules

A

Easily tampered
Sensitivyt to humidity
Unsuitable for aqueous liquids
Unsuitable for highly soluble ionic slats

18
Q

Diluents

A 
Lactose
Microcrystalline cellulose
Starch
Sucrose
Mannitol
Dibasic Calcium Phosphate
19
Q

Disintegrants

A

Pregelatinized Starch
Croscarmellose
Sodium Starch Glycolate

20
Q

Lubricants

A 
Fumed Silicon Dioxide
Magnesium Stearate
Calcium Stearate
Stearic Acid
Talc
21
Q

Surfactant

A

Sodium Lauryl Sulfate

22
Q

Advantages of Tablets

A 
Accurate dosage
Absence of Alcohol
Concentration Variability
Elegance
Patient Acceptance
Convenience
Tamper Resistant
23
Q

Disadvantages of Tablets

A

Swallowing
Difficult to extemporaneously prepare
Compression
oxygen/moisture-sensitivie

24
Q

Binders

A 
Acacia
Alginic Acid
Carboxymethylcellulose
Gelatin
Liquid Glucose
Methylcellulose
Povidone
Pregelatinized Starch
25
Q

Antiadherents

A

Talc

Magnesium Stearate

Pharmaceutics 1 (6 decks)

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