cervical pathology

Question 1

most common cervical infection

Answer 1

HPV - likes squamous epithelium (HPV infection –> squamous intraepithelial lesion –> dysplasia –> cervical carcinoma

High risk types: 16+ 18

Question 2

what part of the cervix is most vulnerable and why

Answer 2

transformation zone: border between metaplastic squamous epithelium and simple columnar epithelium

basically, the proliferating basal layer of metaplastic squamous epithelium is exposed and vulnerable to HPV infection

endocervix (simple columnar epithelium with mucous producing cells) –> ectocervix (stratified squamous epithelium)

Question 3

LGSIL

Answer 3

low grade squamous intraepithelial lesion: proliferation of HPV infected squamous cells –> visible lesion