Cervical cancer Flashcards by Hugh Murray | Brainscape

Q

What are risk factors?

A

HPV infection
Smoking
Immunosuppression

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Q

What percentage of cancer is related to HPV?

A

95%

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Q

Which are the most common HPV types?

A

16 and 18

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Q

How do you stage disease?

A

Clinical

Ix - PET and MRI

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Q

What is the role of surgery?

A

Small lesions only

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Q

What is the first line Rx for locally advanced?

A

Chemoradiotherapy

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Q

Which chemo regimen is used first line?

A

Cisplatin-Gemcitabine

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Q

What is the median survival for advanced disease?

A

12-13 months

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Q

Which biological has been used?

A

Bevacizumab

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Q

What is first line for metastatic cervix Ca?

A

Carboplatin-Paclitaxel + Bevacizumab

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