Cerebral Palsy Flashcards
What is the most common form of spastic CP?
Diplegia
Diplegia primarily affects?
Lower extremities
What causes diplegia?
infarct in the white matter of periventricular area caused by hypoxia
What is the cognitive state associated with diplegia?
Normal cognition
What is the definition for Cerebral Palsy?
“A group of permanent disorders of the development of movement and posture, causing activity limitations that are attributed to non-progressive (nerve lesion) disturbances that occurred in the developing fetal or infant brain”
Why is Cerebral Palsy termed non-progressive?
Because the lesion does not get worse/progress – but movement symptoms can progress with age
Types of movement disorders associated w/ CP (5):
Athetoid, Dyskinetic, Ataxic, Spastic, Hypotonic
Spastic movement disorder
Increased resistance to passive movement which increases with increased velocity of movement
Hypotonic movement disorder
Some infants present with hypotonia w/ transition to spasticity or ataxia
Dyskinetic movement disorder
Uncontrolled movement
Athetoid movement disorder
Slow, writhing movement
Ataxic movement disorder
Balance and control disorder
Classification of parts of the body affected by CP:
Diplegic (legs are more affected); Hemiplegic (one side of the body); Quadriplegic/tetraplegic (all four limbs)
Spastic CP results from what kind of damage to brain?
pyramidal
Dyskinetic and ataxic CP results from what kind of damage to brain?
Extrapyramidal
Type of CP resulting from lesion in cortex, basal ganglia, and cerebellum:
Cortex = Spasticity
Basal Ganglia = Athetosis
Cerebellum = Ataxic
What is the etiology of CP?
Changes in prenatal brain developent
Congenital brain anomalies
There are 3 events in time in which CP can develop. Name those. Which is most common?
- Prenatal Events (prior to birth)
- Perinatal events (during birth)
- Post/neonatal events (after with no upper age limit)
Prenatal and Perinatal events are most common
Is CP easy to diagnose?
Difficult due to plasticity of the developing brain
At what age can CP be diagnosed?
CP is not diagnosed until age 3 and up to age 5
What is the typical presentation for Infants with CP?
Abnormal muscle tone
Atypical posture
Movement with persistent reflexes
Non-progressive (lesion)
What are other diagnoses that can mimic CP
Metabolic disorders (protein breakdown) Mitochondrial disorders
What are the 4 Neuroimaging available for pts with CP?
- Intraventricular hemorrhages
- Germinal matrix hemorrhages
- Periventricular intraventricular hemorrhages
- Periventricular cyst
What can you see with Intraventricular hemorrhages?
bleeding into the ventricles
What happens in Germinal matrix hemorrhages
bleeding into the tissue AROUND the ventricles
Where are you bleeding in Periventricular intraventricular hemorrhages?
Bleeding into BOTH AREAS. (into and around the ventricles)
the name gives you a subtle hint
Can neuroimaging be the only predictive for the development of CP
NOPE! Not singly predictive predictive for the development of CP
Risk factors for development of CP
Injury during critical periods of brain development.
Periventricular wite matter is most sensitive to insult and injury between 24-34 wks of gestation
Risk factors for development of CP antenatal
Prematurity and LBW
Intruterine infections
Multiple gestation
Pregnancy complications
Risk factors for development of CP perinatal
Birth asphyxia
Complicated labour and delivery
Risk factors for development of CP postnatal
Non-accidental injury
Head trauma
Meningitis/encephalitis
Cardiopulmonary arrest
CP is caused by…..
An insult to the developing brain
CP is often accompanied by what other disturbances?
- Sensation and sensory processing involvement
- Perception
- Cognition
- Communication and speech issues
* ** CP may include all of these, just one, or a combination.
Over the last 40 years has the prevalence of CP gone up?
No, it has remained steady
Compared to the past increased survival of _________ &; _____ _______ has been seen.
Preterm; Very Preterm
What birth has the highest likelihood of producing a CP child? Why?
Triplets.
When multiple babies are in the womb, the placenta has to accommodate/deliver more nutrients and oxygen to the babies. In triplets, the placenta acts as if there are 2 babies, instead of 3, so there is an increased chance one child will not get enough oxygen and have CP.
What areas of the body are affected with hemiplegia?
UE and LE on the same side of the body
What areas of the brain area affected in hemiplegia?
Periventricular white matter abnormalities and cervical-subcortical lesions
Describe cognitive function in patients with hemiplegia
normal; social and emotional deficits are prevalent
Describe equipment requirements for patients with hemiplegia
minimal equipment needed
What areas of the body are affected with quadriplegia?
volitional muscle control of all four extremities are severely impaired
Where is the lesion located in patients with quadriplegia?
Periventricular white matter lesions
During a comprehensive assessment for an infant/child with CP, you are looking to identify abnormalities in what 4 areas?
- Motor attainments
- Neurological signs
- Primitive reflexes
- Postural reactions
The purpose of the assessment is to:
- Discover functional abilities & strengths
- Determine primary and secondary impairments
- Discover the desired functional & participation outcomes of the child and/or family.
- Use an organized approach order to get an accurate baseline of the child’s functional abilities
Give an example of a primary impairment and secondary impairment.
Primary - A child cannot use their hand because of spasticity from a lesion.
Secondary - Child has cannot feed themself because they cannot use their hand.
What are postural preparations?
Strategies the child uses before a functional movement & increase stability by changing the BOS or increasing muscle activation around joints
What is the biggest key (for a therapist) during an assessment?
Observation
What is the etiology of CP
- Changes in prenatal brain development
- Congenital brain anomalies
- Prenatal, perinatal, and post/neonatal events
When is CP typically diagnosed?
Not until 3 YO and up to 5 YO
What imaging is used to diagnose CP? What is he preferred method?
MRI–>preferred, provides greatest detail**
Cranial ultrasound-less invasive
CT
What is a typical presentation of an infant with CP?
abnormal muscle tone
atypical posture
movement with persistent reflexes
non-progressive (lesion)
What are other diagnoses that can mimic CP?
Metabolic disorders (protein breakdown) Mitochondrial disorders
What are the 4 types of Neuroimaging? and what can each see?
- Intraventricular hemorrhages (IVH)–>bleeding into the ventricles
- Germinal matrix hemorrhages (GMH)–>bleeding into the tissue AROUND the ventricles
- Periventricular intraventricular hemorrhages (PIVH)–>bleeding into BOTH areas (into and around ventricles)
- Periventricular cyst (PVC)–>form in the area where bleed occurred once the acuteness has resolved
How is the Neuroimaging graded?
I through IV, with IV being the most severe
NOT SINGLY PREDICTIVE FOR THE DEVELOPMENT OF CP
What area of insult is the most sensitive to insult and injury? What weeks of gestation is that?
Periventricular white matter is most sensitive
Between 24-34 weeks of gestation