Cerebral Palsy Flashcards
Three criteria for diagnosis of CP?
1) static brain lesion
2) lesion occurred before birth or first few years of life
3) neuromotor control deficit with altered movement or posture
Greatest risk factor for development of CP?
Prematurity
Are most children with CP born premature?
NO
What are 5 preconception/maternal risk factors for CP?
maternal seizures, maternal thyroid disease, advanced age (>40), obesity, use of reproductive technology, coagulopathy
Most common topographic form of CP?
Hemiplegia (39%)
Does hemiparetic CP typically demonstrate greater impairment in the upper or lower extremity?
upper
What are the 5 different movement patterns seen in CP?
spastic, dyskinetic, hypotonic, ataxic, and mixed
What are the two most common movement patterns seen in CP?
Spastic followed by dyskinetic
At what age can a child be classified with the GMFCS? Why?
Age 2, before this assessments are often inaccurate due to evolving myelination.
GMFCS II
ambulatory but limitation with uneven surfaces and inclines
GMFCS III
use of hand-held mobility device (Lofstrand crutches or rolling walker), may propel a manual wheelchair independently
GMFCS IV
rely mostly on wheeled mobility at home and in community.
GMFCS V
No independent mobility
What ages is the Manual Ability Classification used?
4 to 18
MACS II
slower with manual function but independent with daily activities
MACS III
can complete some activities independently with set-up or assistance
MACS IV
continuous support needed to complete a portion of activity
MACS V
No handling of objects
CFCS II
effective communicator but slower
CFCS III
effective communicator with familiar partners but not effective with unfamiliar partners
CFCS IV
inconsistent communication, even with familiar partners
CFCS V
ineffective communication
What ages is the Eating and Drinking Ability Classification System designed for?
3 and older
EDACS II
needs additional time
EDACS III
some limitation to safety
EDACS IV
significant limitations to safety
EDACS V
unable to eat or drink safely
Most common finding on MRI in children with CP?
PVL
When is a repeat MRI recommended if initial MRI is normal in a child with motor abnormalities?
2 years old
What are 4 primitive reflexes that can be used to evaluate for early CP?
moro, palmar grasp, ATNR, tonic labyrinthine reflex
What are three ways that the 4 primitive reflexes can be highly suspicious for CP?
1) persistence beyond 6 months
2) asymmetric response
3) obligatory response (unable to break out)
At what age do the parachute and lateral protection reactions emerge?
6 months
What ages is the HINE appropriate for?
2 months to 2 years
Optimal HINE scores at 3, 6 and 9 months (not at risk for CP)?
67, 70, 73
What portion of the HINE exam is most predictive?
movement quality and quantity
HINE score at 3-6 months indicating likely GMFCS III or IV
less than 40
HINE score at 3-6 months indicating likely GMFCS I or II
40 - 60
What HINE score at 3 months is highly sensitive and specific for development of CP?
56
Up to what age can the General Movement Assessment be used?
5 months
When is the infant “writhing period”
from preterm to 6-9 weeks
When is the infant “fidgety period”
9 to 20 weeks
How are abnormal fidgety movements characterized?
larger amplitude with moderately exaggerated speed and jerkiness
What assessment is the reference standard for early detection for CP?
GMA
What are three indications for genetic testing in suspected cases of CP?
1) neuroimaging is non-revealing
2) family history of childhood neurologic disorder
3) developmental deterioration
What should be suspected in a previous healthy child with acute encephalopathy without explanation?
metabolic disorder
What imaging findings are more common in children with intellectual disabilities?
gray matter injuries and malformations
What are 5 risk factors for recurrent admission due to respiratory illness in children with CP?
GMFCS IV, dysphagia, seizures, snoring, recent respiratory admission
What are three strategies to address frequent aspiration?
saliva control, g-tube placement with fundoplication, and thickening of feeds
Three treatments for impaired mucociliary clearance?
saline, bronchodialators, chest PT
What is the most common foot deformity in CP?
Equinovalgus
What degree spinal curves are likely to progress?
Greater than 40
What are five risk factors for progression of a spinal curve?
spasticity, quadriparesis, younger age, poor sitting balance, pelvic obliquity
What is the most common upper extremity contracture in CP?
thumb-in-palm
What is the most important outcome to predict satisfaction after surgical correction of an upper extremity contracture?
cosmesis
Most common type of pain in GMFCS I, II?
headaches
Most common type of pain in GMFCS IV, V?
back pain