Cerebellum

Question 1

Name the 3 layers of cellular organisation from deep to surface

Answer 1

Granular
Purkinje
Molecular

Question 2

Name the 3 lobes of the cerebellum

Answer 2

Anterior
Posterior
Flocculonodular

Question 3

Name the 3 deep cerebellum nuclei and what they mean

Answer 3

Dentate (sharp edges)
Fastigial (near 4th ventricle)
Interpostisus (in between) emboliform and globose

Question 4

Main fibres of sup cerebellar peduncle

Answer 4

MOSTLY EFFERENT: red nucleus and sup. Colliculus, dentate-thalamic

Question 5

Main fibres of medial cerebellar peduncle

Answer 5

Main input into cerebellum

CORTICO-PONTINE-CEREBELLAR FIBERS

Question 6

Main fibers of inf. cerebellar peduncle

Answer 6

Mostly AFFERENTS

posterior spinocerebellar tracts
Cuneocerebellar
Reticulocerebeller
Vestibulocerebellar
Olivocerebellar

Some efferents
Cerebello-olivary
Ceribello-reticular fibers
Ceribello- vastibular

Question 7

Name the 2 neuro pathways into the cerebellum from the cortex

Answer 7

Motor cortex & parietal -> internal capsule -> pontine nuclei -> DECUSSATE -> MIDDLE CEREBELLAR PEDUNCLE

OR

motor cortex & parietal -> internal capsule -> red nucleus -> inferior olive -> DECUSSATE -> INFERIOR CEREBELLAR PEDUNCLE

Question 8

Which is the only EFFERENT tract not projected from the deep cerebellar nucleus ?

Answer 8

Vestibular nucleus

Question 9

Name the 2 main EFFERENT cerebellar tracts

Answer 9

Deep cerebellar nuclei -> superior cerebellar peduncle -> DECUSSATE -> superior colliculus

AND

deep cerebellar nuclei -> superior cerebellar peduncle -> DECUSSATE -> VL, VA THALAMUS -> primary and pre motor cortex

Question 10

Describe the spino cerebellar function group and nuclei

Answer 10

Spinocerebellar (paleo in between)

Intermediate/ lateral region:
Distal limb movement (walking) interpose nucleus and red nucleus

Vermis region:
Proximal trunk muscles and eye movements
Fastigule (vestibular complex and reticular formation)
And vestibular

Question 11

Describe the cerebrocellebelar function group and nuclei

Answer 11

(Neo)

Lateral hemisphere
Co-ordination of parietal and temporal movements -INCLUDING SPEECH

dentate nucleus -> thalamus

Question 12

Vestiublocerebellar

Answer 12

Archi

Flocculonodular lobe

Receives input from vestibular nuclei
Posture , balance and eye movement

Question 13

Neuro transmitter of basket, golgi and stellate cells? And function

Answer 13

GABA fine tune movement

Question 14

Describe the print of climbing branches and Purkinje

Answer 14

1:1 ratio of climbing fibers wrapped around Purkinje axon fibers

Question 15

Neurotransmitter of granular layer

Answer 15

Glutamate

Question 16

Purkinje neuro transmitter

Answer 16

GABA

Question 17

Name which two fibers will also directly excite the deep cerebellar nuclei ?

Answer 17

Mossy and climbing

Question 18

Where does the cortico-inhibitory loop occur

Answer 18

Near outer loop

Question 19

Describe missy fiber route

Answer 19

Will project from pontine nuclei .
Cortex , vestibular and spinal cord connections
Enter through inferior peduncle

Question 20

Which is the only output neuron of the cerebellar cortex

Answer 20

Purkinje

Question 21

Where does the Purkinje fibers project to?

Answer 21

Deep cerebellar nuclei

Some lateral vestibular connections

Question 22

Match the output centres to the deep cerebellar nuclei

Thalamus
Red nucleus
Reticular nuclei and vestibular complex

Answer 22

Dentate (thal)
(Interpostius (red)
Vestibular complex and reticular nuclei (fastigilal)

Question 23

Name some pathology related to cerebellum and are they ipsi or contralayeral

Answer 23

Ipsi

NO sensory loss

A synergy
Decomposition of movements - e.g touching nose
Tremors
Ataxia and GAIT problems