Cerebellum Flashcards

1
Q

Cerebellum

A

Receives inputs of almost all sensory modalities

*** critical role in motor control

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2
Q

Cerebellar organization

A

Cerebellar cortex is much folded

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3
Q

Spinocerebellum

A

*** receives proprioceptive & other sensory inputs from all the body parts through spinal cord

receives proprioceptive & other sensory inputs from all the body parts through spinal cord

receives proprioceptive & other sensory inputs from all the body parts through spinal cord

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4
Q

Vermis

A

Controls posture (axial/proximal limbs)

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5
Q

Paravermis

A

Skilled voluntary movements

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6
Q

Vestibulocerebellum

A

Concerned with equilibrium & learning induced changes in vestibulo-ocular reflex

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7
Q

Cerebrocerebellum

A

Involved in planning & programming of the movements as it interacts with the cortex

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8
Q

Basket Cells

A

Inhibitory interneurons in the cerebellar cortex whose cell bodies are located within the Purkinje cell layer

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9
Q

Granular Cell Layer

A

Contains interneurons – granule cells && Golgi cells

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10
Q

Golgi cells

A

provides inhibitory feedback to the granule cells

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11
Q

Granule cells

A

receive inputs from mossy fibers

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12
Q

Cerebellar Functions

A
  • Control of postural balance & equilibrium
  • Vestibulo-ocular reflex
  • Smoothes & coordinates movement
  • Control of skilled voluntary movements
  • Planning & programming of the movements
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13
Q

Internal Circuitry

A
  • Control of muscle tone & stretch reflex
  • Control of movement of one side of body
  • Learning & improvement of motor skill
  • Eye ball movement
  • Vestibular functions
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14
Q

Lesion of flocculonodular lobe

A

Abnormalities in maintaining equilibrium (motion sickness)

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15
Q

Cerebellum Disorders

A

*** hypotonia

Inability to carry out long-term adjustment in motor response

Defect in vestibulo-ocular reflex leads to pathological nystagmus

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16
Q

Charcot’s neurologic triad

A

Nystagmus

intention tremor

scanning speech

disseminated sclerosis

17
Q

Friedreich’s ataxia

A

causes progressive damage to the nervous system

resulting in symptoms ranging from gait disturbance to speech problems

18
Q

Cerebellar Ataxia

A

Defect in coordination due to errors in the rate, range, force, & direction of movement

  • only cerebellar cortex is involved, ataxia is temporary.
  • If the lesion involves deep cerebellar nuclei, ataxia is permanent
19
Q

Cerebellar Ataxia Features

A
  • Drunken gait
  • Scanning speech
  • Dysmetria
  • Intention tremor
  • Rebound phenomenon
  • Adiadochokinesia (Dysdiadokinesia)
  • Decomposition of movement
20
Q

Anterior vermis syndrome

A

Involves the lower limb region of the anterior lobe

atrophy of the rostral vermis—most commonly caused by alcohol abuse

Results in gait, trunk, and leg dystaxia

21
Q

Posterior vermis syndrome

A

Involves the flocculonodular lobe

Usually the result of brain tumors in children

Most frequently caused by medulloblastomas or ependymomas

Results in truncal dystaxia

22
Q

Hemispheric syndrome

A

Usually involves one cerebellar hemisphere

Frequently the result of a brain tumor or an abscess

Results in arm, leg, trunk, and gait dystaxia

Results in cerebellar signs that are ipsilateral to the lesion

23
Q

Romberg’s test

A

tests proprioception, vestibular function, and vision

not a test of cerebellar function

24
Q

Romberg’s test is positive if

A

the patient sways or falls while the patient’s eyes are closed