Cerebellum Flashcards
1
Q
Vermis
A
- Midline cerebellar zone
- Deep nuclei: Fastigial, vestibular
- Balance, eye movement, reflexes
- Autonomic arousal, limbic regulation
2
Q
Paravermal hemisphere
A
- Intermediate cerebellar zone
- Deep nuclei: globose, emboliform
- Sensorimotor integration, movement execution
- Simple verbal responses to commands
3
Q
Lateral hemisphere
A
- Lateral cerebellar zone
- Deep nuclei: dentate
- Preparation and planning of movements, fine motor dexterity, eye movements, imagined movements
- Verbal association, rule-based learning, working memory, problem-solving, monitoring performance, temporal perception
4
Q
Spinocerebellum
A
- Vermis and paravermal hemispheres
- More inputs from spinal cord than other areas
5
Q
Vestibulocerebellum
A
- Flocculus
- More inputs from vestibular nuclei than other areas
6
Q
Cerebrocerebellum
A
- Lateral hemispheres
- More inputs from cerebral cortex (via pontine nuclei) than any other areas
7
Q
Three basic elements of the cerebellum
A
- Cerebellar cortex with a granule, purkinje, and molecular layers
- Deep cerebellar nuclei
- Large white matter tracts
8
Q
Six main cell types in cerebellar cortex
A
- Granule*
- Golgi*
- Purkinje*
- Stellate
- Basket
- Lugaro
9
Q
Two main types of neurons in the deep cerebellar nuclei
A
- Projection neurons
- Local interneurons
10
Q
Non neuronal cells in the cerebellum
A
- Radial or Bergmann glial cells–purkinje and molecular layers of cerebellar cortex
- Bushy astroglia–granule layer
- Oligodendrocytes–white matter
11
Q
Purkinje cell
A
- Connects the inferior olive to the purkinje layer via climbing fibers
- Connects granule cells to purkinje layer via parallel fibers
- Projects to deep nuclei
- Inhibitory neuron
- GABA, GAD, GABA-T, zebrin, motilin
12
Q
Basket cell
A
- Connects granule cells to purkinje layer via parallel fibers
- Projects to purkinje cell somas
- Inhibitory
- GABA, GAD
13
Q
Stellate cell
A
- Connects granule cells to purkinje layer via parallel fibers
- Projects to purkinje cell dendrites
- Inhibitory
- GABA (?)
14
Q
Golgi cell
A
- Connects granule cells to granular layer via parallel fibers
- Projects to granular layer cells
- Inhibitory neuron
- GABA
15
Q
Granule cell
A
- Connects pontine and brainstem nuclei to granular layer via mossy and mossy-like fibers
- Projects to dendrites of other cerebellar cortical cells
- Excitatory!
- GABA, glutamate