Cerebellum Flashcards

1
Q

function of the cerebellum

A

control centre for coordination of voluntary muscle activity, equilibrium and muscle tone of the SAME side

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2
Q

why does a person with cerebellar injury not become paralysed

what effects does injury cause

A

it does not initiate movement

movements are slow, clumsy, tremulous and uncoordinated
hypotonic muscles
unable to walk steadily

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3
Q

what steady stream of information does the cerebellum need to receive

A

position of the body parts in space
equilibrium state of the body
commands being sent from motor cortex to lower motor neurons

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4
Q

how does the cerebellum integrates information

A

by means of feedback pathways

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5
Q

where is the cerebellum located

A

posterior cranial fossa between the cerebral hemisphere and brainstem

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6
Q

primary posterolateral fissures cerebellum

A

divide it into anterior, posterior and flocculonodular lobes

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7
Q

longitudinal divisions of cerebellum

A

into midline vermis and left and right hemispheres

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8
Q

cerebellar cortex role

A

receives inputs

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9
Q

how is the cerebellum connected to the brainstem

A

three bundles of axons

superior, middle and inferior cerebellar peduncle

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10
Q

how is afferent proprioception information from proprioceptive fibres conveyed to cerebellum

A

via dorsal or ventral spinocerebellar tracts
cell bodies of these neurons are in DRGs

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11
Q

how is cerebellar surface area increased

A

folliae []

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12
Q

dorsal spinocerebellar tract route

A

axons from DRG synapse with second-order neurons in dorsal horn
axons ascend on the same side in terminate on the cerebellum of the same side as the DRG

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13
Q

where are second order synapses with DRGs in the dorsal horn

A

upper part of spinal cord
C8-L2

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14
Q

deep cerebellar nuclei

example

A

source of efferent information

dentate nucleus

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15
Q

how does the dorsal spinocerebellar tract enter the cerebellum

A

second-order neurons pass into lateral columns which forms the tract
enters through the inferior cerebellar peduncle

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16
Q

ventral spinocerebellar tract route

A

other axons conveying proprioception from the DRG enter junction and synapse between dorsal and ventral horns
axons cross the midline to ascend on the opposite side but then cross back to enter cerebellum

17
Q

roles of dorsal and ventral spinocerebellar tracts

A

main bundles supplying proprioceptive impulses to the cerebellum

18
Q

how does the cerebellum receive input about head position and rotation

A

from the vestibular apparatus in the inner ear through the vestibulocochlear nerve (CN VIII) `

20
Q

where do fibres that supply information concerning equilibrium state of the body arise

where do they enter the cerebellum

A

superior and vestibular nuclei

through the ipsilateral inferior peduncle

21
Q

function of cortico-ponto-cerebellar pathway

A

when the cerebral motor cortex discharges it brings information about the nature of the discharge to the cerebellum

22
Q

route of corticopontocerebellar tract

A

fibres originate in motor cortex and descend through the internal capsule
synapse on neurons in the pontine nuclei
axons cross the midline and terminate in the cerebellum on the opposite side

23
Q

what information does the cerebellum receive

A

muscle position and tonus
equilibrium
motor discharge to the muscles from the cerebral cortex

24
24
cerebellar projections back via vestibular nuclei route what do these projections cause
cerebellum -> vestibular nuclei -> vestibulospinal tract -> lower motor neurons reflex contraction of axial musculature and proximal limb muscles to maintain balance
25
dentato-rubro-thalamo-cortical pathway function
a pathway which the cerebellum can coordinate movements by feedback pathway to motor cortex
26
dentato-rubro-thalamo-cortical pathway route
dentate nucleus sends fibres that decussate and synapse on red nucleus of midbrain thalamus sends axons that terminate in the motor cortex
26
27
red nucleus projections to lower motor neurons int ventral horn
causes muscle contraction to maintain balance
28
ataxia due to cerebral dysfunction
loss of coordination between muscles patients walks with abnormal gait, feet spread or stumbles
29
asynergia due to cerebral dysfunction
loss of coordination in performing motor acts decomposition of movement - motor acts are jerky
30
dysmetria due to cerebral dysfunction
inability to judge distance and to stop movement at a chosen spot patients over/under reach for objects may hit cheek when asked to touch nose
31
intention tremors in dysmetria
occur during a movement and not at rest
32
effects of cerebellar dysfunction
ataxia asynergia dysmetria intention tremors hypotonia falling
33
medulloblastoma
most common primary CNS tumour in children situated in vermis or root of fourth ventricle characteristic signs are headache and vomiting, ataxia highly malignant but sensitive to radiation 60% 5 year survival