Cephalosporins Flashcards

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1
Q

first generation

A
  • Cephalothin
  • Cephapirin
  • Cefazolin
  • Cephalexin
  • Cephradine
  • Cefadroxil
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2
Q

first generation - all are “ceph” except for…

A

Cefadroxil and Cefazolin

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3
Q

what does the first generation treat? (SAU SEP PNEU and PYO)

A
  • Staphylococcus aureus
  • Staphylococcus epidermidis
  • Staphylococcus pneumoniae
  • Staphylococcus pyogenes
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4
Q

what anaerobic microorganisms can the first generation treat? (ANA STREP AND PECK)

A

anaerobic streptococci + PEck
- Proteus mirabilis
- Escherichia coli
- Klebsiella pneumoniae

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5
Q

only 1st gen used parenterally, DOC for surgical prophylaxis

A

Cefazolin (IV)

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6
Q

second generation

A
  • Cefamandole
  • Cefuroxime
  • Cefonicid
  • Cefaclor
  • Cefoxitin
  • Cefotetan
  • Cefprozil
  • Cefmetazole
  • Cefuroxime axetil
  • Loracarbef
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7
Q

second generation - “cef” not ending in -one or -ime except

A

Loracarbef, Cefuroxime, Cefbuperazone

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8
Q

what does the second generation treat? (SAU PNEU PYO)

A
  • Staphylococcus aureus
  • Staphylococcus pneumoniae
  • Staphylococcus pyogenes
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9
Q

what anaerobic microorganisms can the second generation treat? (ANA STREP AND PECK HEN)

A

anaerobic stretococci + HENPEcK
- Haemophilus influenzae
- Enterobacter aerogenes
- Neisseria gonorrhae
- Proteus mirabilis
- Escherichia coli
- Klebsiella pneumoniae

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10
Q

for CAP (for Haemophilus influenzae, Streptococcus pneumoniae)

A

cefuroxime

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11
Q

third generation

A
  • Ceftizoxime
  • Ceftriaxone
  • Cefotaxime
  • Ceftazidime Cefoperazone
  • Moxalactam
  • Cefixime
  • Cefpodoxime proxetil
  • Ceftibuten
  • Cefdinir
  • Cefditoren
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12
Q

third generation ends in -one or -ime except for…

A

Cefdinir, Ceftibuten, Moxalactam, Cefditoren

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13
Q

what does the third generation treat? (PNEU PY)

A
  • Streptococcus pneumoniae
  • Streptococcus pyogenes
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14
Q

what anaerobic bacteria does the third generation treat? (ANA STREP and HENPPECK)

A

anaerobic streptococci + HENPPEcK
- Haemophilus influenzae
- Enterobacter aerogenes
- Neisseria gonorrhae
- Pseudomonas aeruginosa
- Proteus mirabilis
- Escherichia coli
- Klebsiella pneumoniae

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15
Q

fourth generation

A
  • Cefepime
  • Cefpirome
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16
Q

what does the fourth generation treat? (SAU PNEU PYO)

A
  • Streptococcus aureus
  • Streptococcus pneumoniae
  • Streptococcus pneumoniae
  • Streptococcus pyogenes
17
Q

fifth generation

A
  • Ceftaroline
  • Ceftobiprole
17
Q

fifth generation

A
  • Ceftaroline
  • Ceftobiprole