Cephalosporins Flashcards
first generation
- Cephalothin
- Cephapirin
- Cefazolin
- Cephalexin
- Cephradine
- Cefadroxil
first generation - all are “ceph” except for…
Cefadroxil and Cefazolin
what does the first generation treat? (SAU SEP PNEU and PYO)
- Staphylococcus aureus
- Staphylococcus epidermidis
- Staphylococcus pneumoniae
- Staphylococcus pyogenes
what anaerobic microorganisms can the first generation treat? (ANA STREP AND PECK)
anaerobic streptococci + PEck
- Proteus mirabilis
- Escherichia coli
- Klebsiella pneumoniae
only 1st gen used parenterally, DOC for surgical prophylaxis
Cefazolin (IV)
second generation
- Cefamandole
- Cefuroxime
- Cefonicid
- Cefaclor
- Cefoxitin
- Cefotetan
- Cefprozil
- Cefmetazole
- Cefuroxime axetil
- Loracarbef
second generation - “cef” not ending in -one or -ime except
Loracarbef, Cefuroxime, Cefbuperazone
what does the second generation treat? (SAU PNEU PYO)
- Staphylococcus aureus
- Staphylococcus pneumoniae
- Staphylococcus pyogenes
what anaerobic microorganisms can the second generation treat? (ANA STREP AND PECK HEN)
anaerobic stretococci + HENPEcK
- Haemophilus influenzae
- Enterobacter aerogenes
- Neisseria gonorrhae
- Proteus mirabilis
- Escherichia coli
- Klebsiella pneumoniae
for CAP (for Haemophilus influenzae, Streptococcus pneumoniae)
cefuroxime
third generation
- Ceftizoxime
- Ceftriaxone
- Cefotaxime
- Ceftazidime Cefoperazone
- Moxalactam
- Cefixime
- Cefpodoxime proxetil
- Ceftibuten
- Cefdinir
- Cefditoren
third generation ends in -one or -ime except for…
Cefdinir, Ceftibuten, Moxalactam, Cefditoren
what does the third generation treat? (PNEU PY)
- Streptococcus pneumoniae
- Streptococcus pyogenes
what anaerobic bacteria does the third generation treat? (ANA STREP and HENPPECK)
anaerobic streptococci + HENPPEcK
- Haemophilus influenzae
- Enterobacter aerogenes
- Neisseria gonorrhae
- Pseudomonas aeruginosa
- Proteus mirabilis
- Escherichia coli
- Klebsiella pneumoniae
fourth generation
- Cefepime
- Cefpirome