Central Sensitization Flashcards
1
Q
What is an amplification of neural signaling within the CNS that elicits pain hypersensitivity?
A
Central sensitization
2
Q
How many of adults suffer from chronic pain?
A
40%
3
Q
How many adults suffer from generalized hypersensitivity and conditioned pain modulation?
A
17-35%
4
Q
What are the clinical features of central sensitization?
A
pain (all over body)
fatigue
anxiety/depression
5
Q
During central sensitization, what 2 reasons enhance the sensation of pain?
A
Changes in nerve fibers & environment
Modifications of the functional properties and the genetic programming of primary & secondary afferent neurons
