Ankylosing Spondylitis

Question 1

What is a Chronic inflammatory disease of the SI joints, and spine, Progressive stiffness, and in some cases ankylosis (bony fusion), and a disease of young males?

Answer 1

Ankylosing spondylitis

Question 2

What tissue type has the strongest association to AS (over 95% of patients test positive)?

Answer 2

HLA-B27

Question 3

What has been implicated as the infective agent that initiates an auto-immune response in AS?

Answer 3

Klebsiella aeruginosa

Question 4

What kind of AS shows up before 16 years old, has oligoarthritis, iritis, enthesitis with no spinal involvement?

Answer 4

Atypical/Juvenile AS

Question 5

What kind of AS shows up on an average of 26 years old, has inflammatory back pain, is present for more than 3 months, worsened with overnight rest, and improved with mild to moderate exercise?

Answer 5

Typical AS

Question 6

What is the most common feature of Typical AS?

Answer 6

sacroilitis

Question 7

What is the key central feature of AS?

Answer 7

enthesitis

Question 8

What lab test is a common indicator of inflammation?

Answer 8

ESR