Central Nervous System - Substance Dependence Flashcards

1
Q

is the tx given in mild alcohol dependence?

A

no assistance needed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Where is the tx of moderate alcohol dependence?

A

tx at community unless high risk of developing alcohol withdrawal seizures or delirium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is the tx of severe alcohol dependence?

A

undergo withdrawal in inpatient setting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

tx of alcohol dependence?

A
  • CBT
  • acamprosate
  • naltrexone (alternate = disulfiram)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is the tx of withdrawal symptoms of alcohol dependence?

A
  • long acting benzodiazepines = chlordiazepoxide or diazepam
  • alternate = carbamazepine or clomethiazole
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is tx of delirium

A

lorazepam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is tx of wernick’s encephalopathy

A

thiamine (vit b12)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are the tx of nicotine dependence?

A
  • varenicline
  • bupropion
  • NRT
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

when is bupropion avoided?

A
  • psychiatric illness
  • seizures
  • eating disorders
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what can bupropion cause?

A

serotonin syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

when is varenicline
avoided?

A
  • epilepsy
  • cardiovascular disease
  • psychiatric illnesses
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What formulation of NRT is given?

A

patch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How long is NRT given in pregnant or experiencing nightmares

A

16HR if pregnant or experiencing nightmares

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is the short-term reliver added with NRT patches?

A
  • lozenges
  • gum
  • sublingual tabs
  • inhalator
  • nasal spray
  • oral spray
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are the requirements for opiod dependence tx?

A
  • under qualified prescriber supervision
  • prescribed on FP10MDA
  • max 14DY supply
  • three or more missed doses = specialist reinitation
  • tx continue through pregnancy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is prescribed if there is a high risk of overdose in buprenorphine and methadone?

A

naloxone

17
Q

buprenorphine compared to methadone?

sedating, withdrawal symptoms and risk of overdose

A
  • less sedating that methadone
  • milder withdrawal symptoms
  • less risk of overdose
18
Q

what is suboxone and when is it used?

Active ingredients + when is it used

A
  • buprenorphine with naloxone
  • used when risk of injecting
19
Q

s/e and cautions of methadone

A
  • causes QT prolongation
  • carefully titrated according to pt needs