Central Nervous System - Nausea and Vomiting Flashcards

1
Q

tx + prophylaxis tx of N+V?

A

A
antihistamines (cyclizine + promethazine) or phenothiazines (prochlorperazines)

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2
Q

tx of N+V in pregnancy?

A

avoid tx but if needed use promethazine

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3
Q

post-operative N+V tx?

A

5HT3-receptor antagonist ondansetron or dexamethasone

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4
Q

pre-operative N+V tx?

A

lorazepam

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5
Q

motion sickness N+V tx?

A

hyoscine hydrobromide

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6
Q

terminal illness N+V tx?

A

antipsychotics (haloperidol + levomepromazine)

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7
Q

parkinsons N+V tx?

A

domperidone

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8
Q

why is domperidone ideal in parkinsons?

A

doesnt cross blood barrier brain

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9
Q

daily dose of domperidone?

A

10mg TDS

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10
Q

Age limit if domperidone?

A

12+

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11
Q
A
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12
Q

maximum duration of domperidone?

A

7DY

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13
Q

Minimum weight requirement of domperidone?

A

35+

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14
Q

s/e of domperidone?

A

can cause QT prolongation

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15
Q

why is metoclopramide not ideal in parkinsons?

A

can cause EPSE

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16
Q

what is daily dose of metoclopramide?

A

10mg TDS

17
Q

what is minimum age requirement of metoclopramide?

A

18+

18
Q

what is maximum duration of metoclopramide?

A

5DY

19
Q

MHRA warning of hyoscine hydrobromide patch

A

risk of severe anticholinergic s/e