Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CNSVS1 > Central Nervous System - Psychosis + Schizoprenia > Flashcards

Central Nervous System - Psychosis + Schizoprenia Flashcards

1
Q

what are the +ve symptoms in psychosis + schizophrenia

A

delusions, hallucinations, disorganisations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are the -ve symptoms in psychosis + schizophrenia

A

social withdrawal, neglect, poor hygiene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the 1st gen antipyschotics?

A

phenothiazines
thioxanthenes
butyprohenones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the 2nd gen antipyschotics?

A

ORCQA2
olanzapine
risperidone
clozapine
quetiapine
Aripiprazole
Amisulpride

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

how many groups are they of phenothiazines

A

3 groups

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what are the drugs in 1st gen phenzothiazines group 1

A

chlorpromazine, levomepromazine, promazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the drugs in 1st gen phenzothiazines group 2

A

pericyazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are the drugs in 1st gen phenzothiazines group 3

A

-fluphenazine, prochlorperazine, trifluoperazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

chlorpromazine, levomepromazine, promazine

what is the s/e of Group 1 phenzothiazines

A

most sedation
moderate antimuscarinic + EPSEs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

pericyazine

what is the s/e of Group 2 phenzothiazines

A

-moderate sedation
-least EPSEs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

-fluphenazine, prochlorperazine, trifluoperazine

what is the s/e of Group 3 phenzothiazines

A

-moderate sedation
-high EPSEs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the drugs in 1st gen butyrophenones

A

benperidol + haloperidol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

benperidol + haloperidol

what are the s/e of 1st gen butyrophenones

A

-moderate sedation
-high EPSEs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are the drugs in 1st gen thioxanthies

A

-flupentixol
-zuclopentini**xol **

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

flupentixol, zuclopentinixol

what are the s/e of 1st gen thioxanthies

A
  • moderate sedation, antimuscarinic effects + EPSEs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what are the other drugs in 1st gen?

A

pimozide
sulpride

17
Q

what are the s/e of pimozide + sulpride

A

-reduced sedation, antimuscarinic effects +EPSEs

18
Q

which antipsychotics cause extrapyramidal s/e?

A

group 3 phenothiazines (perazines) + butyropheriones peridol

19
Q

which antipsychotics cause hyperprolactinaemia?

A

all but least in aripiprazole

20
Q

which antipyschotics cause sexual dysfunction?

A

ALL

21
Q

which antipyschotics cause cardiovascular s/e - QT prolongation?

A

pimozide + haloperidol

22
Q

which antipyschotics cause hypertension?

A

clozapine + quetiapine

23
Q

which antipyschotics cause hyperglycaemia

A

CORQ
clozapine
olanzapine
risperidone
quetiapine

24
Q

which antipyschotics cause weight gain

A

olanzapine + clozapine

25
Q

How often should weight be monitored in antipyschotics?

A

weekly for 6WK * 12WK for 1YR * yearly

26
Q

what is tx of neuroleptic maligant syndrome?

A
  • tx should be stopped before tx neuroleptic malignant syndrome
  • tx with bromocriptine resolve in 5-7DY
27
Q

How often should fasting blood glucose/HbA1c + blood lipid conc be monitored?

A

start at 12WK for 1YR * yearly

28
Q

how often should blood pressure be monitored in antipyschotics?

A

start at 12WK for 1YR * yearly

29
Q

how often should ECG be monitored in antipyschotics?

A

before initation only

30
Q

how often should FBC, U+Es + LFT be monitored in antipyschotics?

A

start then yearly

31
Q

what is clozapine used in?

A

resistant schizophrenia

32
Q

when should clozapine be used?

A

only when** 2+ antipyschotics** including 1x 2nd gen has been used for** 6-8WK each**

32
Q

if 2+ doses missed in clozapine what happens?

A

only reinitated by specialist

33
Q

what is monitored in clozapine and how often?

A

leuocyte + differential blood counts
- weekly for 18WK * fornightly for 1YR * monthly

34
Q

what are the s/e of clozapine?

A

-myocarditis + cardiomyopathy
-agranulocytes + neutropenia
-GI disturbances

35
Q

what to do if pt is on clozapine and develops myocarditis + cardiomyopathy?

A

report and STOP if tachycardia

36
Q

what to do if pt is on clozapine and develops agranulocytes + neutropenia?

A

monitor leuocycte and differential blood counts

37
Q

what to do if pt is on clozapine and develops GI disturbances?

A

report on constipation and STOP if intestinal block

CNSVS1 (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions