Central Nervous System -Dementia Flashcards
1
Q
what is dementia?
A
alleviation of high amounts of acetylcholine
2
Q
tx of mild to moderate dementia
A
-acetylcholinesterase inhibitors
->donepezil
->rivastigmine
->galantamine
3
Q
s/e of donepezil
A
neuroleptic malignant syndrome
4
Q
s/e of rivastigmine
A
GI s/e - less in transdermal formulations
5
Q
s/e of galantamine
A
steven-johnsons syndrome
6
Q
tx of dementia moderate to severe
A
memantine
7
Q
what is the aggravation tx of dementia?
A
-benzodiazepines or antipsychotics
8
Q
what does high levels of acetylcholine cause?
A
parasympathetic s/e
9
Q
what are the s/e of dementia tx
A
DUMB-BELLS
Diarrhoea
Urinary incontience
Muscle weakeness
Bradycardia
Bronchospams
Emesis
Lacrimation
Salivation
10
Q
If patient develops dehydration during tx what do you do?
A
stop tx + tx dehydration before reintiating or amending dose
