Central Nervous System Drugs Flashcards

1
Q

Whta is neuropharmacology?

A

It is the study of drugs that alter processes controlled by the nervous system

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2
Q

This is conducting an action potential down the axon of the neuron.

A

Axonal Conduction

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3
Q

This is a process by which information is carried across the gap between neuron and postsynaptic cell

A

Synaptic Transmission

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4
Q

What is the used of Central Nervous System drugs?

A

It is used for psychiatric disorders, suppression of seizures, relief of pain, production of anesthesia.

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5
Q

How many CNS compounds that serve as neurotransmitters?

A

21

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6
Q

What does GABA stands for?

A

Gamma-aminobutyric acid

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7
Q

What is the main purpose of the blood brain barrier?

A
  1. Prevents the sudden influx of the electrolytes, prevents the sudden changes in the concentration of your inside and outside brain, and prevents the burst of cells.
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8
Q

Where does the blood brain barrier is limited?

A

Only to lipid-soluble agents or specific transport systems.

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9
Q

Which is more sensitive to CNS drugs?

A

Children

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10
Q

What could be the effects of using CNS for a long period of time?

A
  1. Increased therapeutic effects
  2. Decreased side effects
  3. Tolerance and physical dependance
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11
Q

It is a hyperactivity disorder. Commonly diagnosed in children

A

ADHD

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12
Q

It is characterized by falling asleep during normal working activities.

A

Narcolepsy

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13
Q

It is a CNS stimulants that stimulate the release of NE and DA from the brain and SNS.

A

Amphetamines

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14
Q

What is the effect of Amphetamine in a person with ADHD?

A

It helps him to be more focus on the task assigned to him.

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15
Q

It is a nervous system disease with slow progressive disorder characterized by tremor, rigidity and slowed movement.

A

Parkinson’s disease

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16
Q

It is to improve the patient’s ability to carry out activities of daily life.

A

Therapeutic goal

17
Q

It is the group of disorders characterized by excessive excitability of neurons in the CNS.

A

Epilepsy

18
Q

What are the drugs for partial focal seizures?

A
  1. Carbamazepine
  2. Gabapentin
  3. Lamotrigine
  4. Tigabine
  5. Topiramate
19
Q

What are the mechanism of anti-epileptic drugs?

A
  1. Suppression of Sodium influx
  2. Suppression of Calcium influx
  3. Antagonism of Glutamate
  4. Protentiation of GABA
20
Q

It is the most commonly prescribed anticonvulsant drug.

A

Phenytoin