Cardiovascular Drugs Flashcards
1
Q
What is Hypertension?
A
Defined as a persistent systolic pressure of greater than 140 mmHG and/or a distolic pressure of greater than 90mmHg.
2
Q
What are the goal of antihypertensive theraphy?
A
- Reduction of cardiovascular and renal morbidity and mortality
- Achieve a normal blood pressure.
- Individualized considering co-morbidities and impact of patient’s quality of life
3
Q
What are the anti-hypertensive?
A
- Diuretics
- Adrenergic drugs
- Direct vasodilators
- ACE inhibitors
- Calcium channel blockers
- Direct renin inhibitors
- Angiotensin receptor blockers
4
Q
What is diuretics?
A
Drugs that can accelerate the rate of urine frmation that results to the removal of sodium and water from the body.
5
Q
What are adrenergic drugs?
A
- Central acting- acts on the brain by decreasing NE production
(Drugs: Clonidine, Methyldopa) - Peripheral acting- at the heart and blood vessels
(Drugs: Aplha and beta blockers)
6
Q
What is the adverse effect of adrenergic drug?
A
- Postural hypotension
- Bradycardia
- Dry mouth
- Dizziness
7
Q
What are the indications of ACEI?
A
- Hypertension
- Adjunct for heart failure
- Stop progression of LVH
8
Q
Mechanism of action of Angiotensin II Receptor Blockers?
A
Block binding of Angiotension II to its receptors and primarily affects the vascular smooth muscle and adrenal gland.
9
Q
What are the three types of calcium channel blocker (CCB)?
A
- Phenylalkylamines - Verapamil
- Benzothiazepines - Diltiazem
- Dihydroyrines - Amlodepine, Nicardepine, Nifedipine
10
Q
What are the adverse effect of CCB?
A
- Hypotension
- Palpations
- Constipation
- Nausea
- Peripheral edema
