Cellular Regulation Flashcards

1
Q

The process of RBC production is called what?

A

Erythropoeis

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2
Q

Erythropoietin is primarily produced by what?

A

Kidneys

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3
Q

The life span of a RBC is about?

A

120 days

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4
Q

What is a hormone secreted by the kidneys that increases the rate of production of RBC’s in response to falling levels of oxygen in the tissues?

A

Erythropoietin

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5
Q

What is the term used to describe the average volume of RBC’s?

A

Mean Corpuscular Volume (MCV)

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6
Q

What is the term used to describe the percentage of RBC’s that contains hgb?

A

Mean Corpuscular Hemoglobin Concentration (MCHC)

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7
Q

What are reticulocytes?

A

Immature RBC’s

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8
Q

If hct is increased what should you assess for?

A

Dehydration

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9
Q

If hgb is decreased what does that mean?

A

Decrease oxygen to the tissues

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10
Q

Hyperplasia is sometimes a normal alteration in what?

A

Cell growth

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11
Q

The cellular alteration where a cell loses the appearance of the parent cell is known as what?

A

Anaplasia

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12
Q

What is the term used to describe any new mass of cells that has no physiological purpose?

A

Tumor

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13
Q

What is the term for programmed cell death and occurs in normal cells?

A

Apoptosis

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14
Q

The ability of a cancer cell to travel and grow in another part of the body is referred to as what?

A

Metastasis

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15
Q

The average lifespan of a WBC is what?

A

12-18hrs

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16
Q

The time it takes for a stem cell to mature into a neutrophil is?

A

10-14 days

17
Q

What is the main function of RBC’s?

A

To carry oxygen t/o body

18
Q

What are normal hct levels?

A

Men: 39-50%; Women: 35-45%

19
Q

What are normal WBC levels?

A

4,500-10,000mcl

20
Q

What is a normal platelet count?

A

150,000-400,000mcl

21
Q

What are normal hgb levels?

A

Men: 14-18g/dl; Women: 12-16g/dl

22
Q

What are alterations in cellular regulation?

A

Deficient cell production
Defective production of cells
Destruction of cells
Excessive blood loss

23
Q

What is the term used to describe an increase in # or density of normal cells?

A

Hyperplasia

24
Q

What is the term used to describe a cell is normal for its type but not in its normal location?

A

Metaplasia

25
Q

What is the term used to represent a loss of DNA control over differentiation occurring in response to adverse conditions?

A

Dysplasia

26
Q

What is the term used to describe the regression of a cell to an immature or undifferentiated cell type?

A

Anaplasia