Cellular Neuroscience II Flashcards
How is chemical transmission achieved?
via the release and binding of NT to the post-synaptic neuron
What is the role of dopamine?
Higher-order cognitive functions
Voluntary movement
reward/reinforcement learning
what is the role of norepinephrine?
cognitive arousal/attention
Memory and flexibility
Mood
what is the role of acetylcholine?
Learning and short-term memory
long-term potentiation (retrieval of memory)
sensory processing/attention
Movement
what is the role of serotonin?
Mood
Challenge caused when modulating NT levels
“pure insertion is too simple” there are interactions with other NT. an individuals baseline level of NT should fall in the peak of the curve.
Where is dopamine created?
Substantia nigra and ventral tegmental area (VTA)
Dysfunctional levels associated with dopamine are
Parkinson’s disease
Psychotic thoughts
Addiction
where is norepinephrine created?
Locus coeruleus
Dysfunctional levels associated with norepinephrine are
Alzheimer’s disease
Mood disorders
Visuospatial neglect
Where is serotonin created?
raphae nucleus
Dysfunctional levels associated with serotoninare
Mood disorders
psychotic thoughts
where is acetylcholine created?
Basal forebrain
Masopontine tegmentum
Dysfunctional levels associated with acetylcholine are
Alzherimer's disease Myasthenia gravis (muscle contractions/relaxations)
