Cellular Mech of learning and memory Lec 14 Flashcards

1
Q

HM

A

Suffered from epilepsy
Had surgery
A lot involved

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2
Q

RB

A

Bouts of anoxia due to cardiac arrest
less involved than HM
Damage to CA1 of hippocampus

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3
Q

Rodents study

A

Showed spatial learning and memory depends on the hippocampus

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4
Q

Studies of HM, RB, and others

A

Formation of declarative memories depends on the hippocampus and its subcortical connections to the mammillary bodies and dorsal thalamus

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5
Q

Declarative short term

A

Hippocampus and related structures

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6
Q

Declarative long term

A

Cortical sites

  • Wernicke’s area for meaning of words
  • Temporal cortex for the memories of objects and faces
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7
Q

Nondeclarative short term

A

Widespread

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8
Q

Nondeclarative long term

A

Cerebellum
Basal ganglia
Premotor cortex

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9
Q

LTP protocol

A

Basline- low freq and low intensity- AMPA receptors

High freq and high intensity- NMDA receptors

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