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Week 1 > Cells and Fibers of the Body > Flashcards

Cells and Fibers of the Body Flashcards

1
Q

4 basic tissue types

A

Epithelium
Muscle
Nervous
Connective Tissue

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2
Q

Connective tissue consists of 2 components

A

Cells

ECM

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3
Q

ECM consists of 2 components

A

Ground substance

Fibres

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4
Q

5 fixed cells

A 
Fibroblasts/cytes
Adipocytes
Plasma cells
Mast cells
Macrophages
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5
Q

5 Wandering cells (can be both though)

A 
Lymphocytes
Neutrophils
Eosinophils
Basophils
Monocytes
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6
Q

Fibroblast/cyte function

A

Maintain integrity of tissues with slow, continuous turnover of ECM

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7
Q

B cells

A

Mature in bone marrow
Enter blood
Can be activated by antigen and become plasma cells or memory B cells
Humoral immunity

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8
Q

T cells

A

Leave bone marrow and mature in thymus

Involved in cell mediated/adaptive immunity

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9
Q

NK cells

A

Mature in bone marrow, lymph nodes, spleen, tonsils, thymus
Kill virally infected cells and tumours
Innate immune response

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10
Q

Mast cells

A

Found in all connective tissues (esp skin, GI lining, around blood vessels)
Allergic response
Synthesize and secrete heparin and histamine

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11
Q

Names for macrophages in

  1. Liver
  2. Skin
  3. Bone
A
  1. Kupffer cells
  2. Langerhans cells
  3. Osteoclasts
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12
Q

What cell type is the first responders

A

Neutrophils

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13
Q

Pneumonic showing the order of which WBCs are most abundant in blood

A

Never Let Monkey Eat Banana

Blood under normal physiological conditions

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14
Q

Function of monocytes/macrophages

A 
Tissue scavengers (phagocytosis)
Defense
Cleaning house
Importnat in immune mechanisms
Often first to contact antigens
Antigen presenting cells
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15
Q

Neutrophil functions

A

Phagocytes

Defense against bacteria

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16
Q

Eosinophil functions

A

Combat parasites

Involved in allergies and asthma

17
Q

Function of basophils

A

Recruited into tissues where allergic reactions are occurring

18
Q

3 types of fibers in CT matrix

A

Collagen
Reticular
Elastic

19
Q

Collagen fibers

A

Made of type 1 collagen
Produced by fibroblasts
Stain eosinophilic

20
Q

Function of

  1. Loose CT
  2. Dense Irregular CT
  3. Dense Regular CT
A
  1. No strength, binding of tissues and providing medium for oxygen and nutrient diffusion
  2. Allows stretching in diff directions
  3. Highly organized, tensile strength
21
Q

Reticular fibers

A

Type 3 collagen

Supporting network for myeloid and lymphoid tissues

22
Q

Elastic fibers

A

Covalent linkage of elastin proteins

Stretch and recoil

Week 1 (12 decks)

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