Cell Wall Inhibitors ( Fosfomycin )

Question 1

Fosfomycin is a derivative of ……………….

Answer 1

Phosphoric acid

Question 2

MOA of fosfomycin :

Answer 2

Inhibit the first step in peptidoglycan synthesis by inhibiting the enzyme UDP-N-acetylglucosamine enolpyruvul transferase

Question 3

Fosfomycin is a first line therapy ……………. :

Answer 3

Acute cystitis

Question 4

……………….. is unlikely with fosfomycin

Answer 4

Cross-Resistance