cell to cell communication Flashcards

1
Q

describe endocrine cell signalling

A

hormones secreted into bloodstream, and travel to distant cells/organs

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2
Q

describe paracrine cell signalling

A

cells secrete hormone which is distributed locally

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3
Q

describe synaptic cell signalling

A

neurotransmitter released into synapse to carry electrical signal from one cell to another

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4
Q

describe ion gated cell signalling

A

receptor on ion gated channel, when a ligand bind it will cause a change in structure of channel

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5
Q

what conditions are associated with damage to ion gated cell signalling

A

epilepsy
cardiac dysfunction

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6
Q

describe G-protein coupled cell signalling

A

transmembrane receptor, ligand bind to outside, causing the inside component of receptor to bind to GTP, converting it to GDP and causing cellular change

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7
Q

describe enzyme linked cell signalling

A

ligand binds to 2 adjacent receptors, they phosphorylate eachother creating reaction cascade which will eventually be terminated by signalling GTP proteins or protein phosphorylsation

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8
Q

describe the 2 types of contact cell signalling

A

gap auctions between 2 connected cells

signalling molecule of cell surface of one cell, relying on contact with receptor on cell surface of another cell

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9
Q

what condition would be associated with damage to enzyme linked cell signalling

A

cancer- no RAS to stop cell signalling, constant reproduction

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10
Q

what condition is associated with damage to production of G proteins in G protein coupled receptor cell signalling

A

pseudohyploparathyroidism

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11
Q

what condition is associated with reduced signal initiation in G protein coupled receptor cell signalling

A

whooping cough

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12
Q

what condition is associated with increased signal initiation in G protein coupled receptor cell signalling

A

hypertension

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