Cell Signaling Introduction Flashcards
What are three basic steps of cell signaling?
1) reception
2) transduction
3) response
The molecule that is effected by the response
effector mlecules
List different changes in the state of proteins.
1) on-off switch
2) modification mode on protein (PTMs)
3) sum of various inputs (emergent properies)
List different signaling currencies.
1) binding/dissociation
2) post-translational modification
3) conformational change
4) localization
What signaling currency is this?
binding/dissociation
What signaling currency is this?
post-transcriptional modification
What signaling currency is this?
conformational change
What signaling currency is this?
localization
What does this state change depict?
inactivating phosphorylation on pTyr527
What does this state change depict?
activating phosphorylation on Tyr416 on the activation loop
Which cellular information processing system is this?
molecular signaling device
Which cellular information processing system is this?
network signaling device
Which cellular information processing system is this?
cellular signaling device
