Cell Signaling/ DNA Structure and Replication-Week 10

Question 1

Which of the following DNA sequences is complementary to 5’ ATGGTCAGT 3’?

5’ ATGGTCAGT 3’
5’ TACCAGTCA 3’
5’ TGACTGGTA 3’
5’ ACTGACCAT 3’

Answer 1

5’ ACTGACCAT 3’

Question 2

DNA replication always proceeds by adding new bases to the _________ end of an existing strand.

5’
3’
2’
4’

Answer 2

3’

Question 3

Watson and Crick developed a model of DNA in which the two strands twist into the shape of a _________.

double pleated sheet
circle
double helix
helix

Answer 3

double helix

Question 4

Because the two strands of a DNA molecule are _________ to each other, either one can be used as a template to reconstruct the other.

identical
bound
antiparallel
complementary

Answer 4

complementary

Question 5

In synaptic signaling, neurotransmitters are released into a space that is referred to as a:__________________.

paracrine space.
neuron junction.
gap junction.
chemical synapse.

Answer 5

chemical synapse

Question 6

If a mutation prevented synthesis of the beta subunit of DNA pol III, which would be most affected?

Formation of RNA primers
Removal of RNA primers
Processivity
DNA unwinding

Answer 6

processivity

Question 7

Avery and his coworkers showed that the agent responsible for changing nonvirulent bacteria into virulent bacteria was __________________.

DNA.
polysaccharide.
lipid.
RNA.

Answer 7

DNA

Question 8

If a short sequence of DNA is 5’ AATTGCCGT 3’, its complement is _______________.

3’ TTAAGCCGA 5’.
3’ TTAACGGCA 5’.
5’ AAAACGCCA 3’.
3’ TTAACGGCT 5’.

Answer 8

3’ TTAACGGCA 5’.

Question 9

Endonucleases and exonucleases are enzymes that can remove nucleotides from a polynucleotide chain. An endonuclease removes nucleotides _______ while an exonuclease removes nucleotides _________.

internally; from the ends of the chain.
from the ends of the chain; internally
from the 3’ end of the chain; from the 5’ end of the chain
from the 5’ end of the chain; from the 3’ end of the chain

Answer 9

internally; from the ends of the chain.

Question 10

In Griffith’s experiments, ______________________.

mice infected with heat-killed virulent bacteria and heat-killed nonvirulent bacteria developed pneumonia and died.
mice infected with live nonvirulent bacteria developed pneumonia and died.
nonvirulent bacteria transformed the virulent bacteria into a nonvirulent variety.
mice infected with heat-killed virulent bacteria and live nonvirulent bacteria developed pneumonia and died.

Answer 10

mice infected with heat-killed virulent bacteria and live nonvirulent bacteria developed pneumonia and died.