cell membranes Flashcards
why do cell membranes have to be partially permeable ?
they have to allow substances in to be used and let substances out in order for normal function of the cell to continue
what are 6 roles of the cell membrane?
separates cell components from external environment.
regulates transport of substances in and out of the cell.
may contain enzymes involves in a metabolic pathway that are bound to the membrane.
has antigens, allows immune system to recognise the cell and not attack it.
may release chemicals to signal to other cells and could contain receptors to receive chemical signals from other cells.
site of chemical reactions
what is the role of membranes around organelles?
to separate contents of the organelle from the cytoplasm
what does the fluid mosaic model explain about the membrane ?
how cell membrane is dynamic and interacts with the cells environment
what is the structure of cholesterol?
it is polar, has hydrophilic group at one end and attracts the polar head of the phospholipids
the rest of it is hydrophobic and attracts the hydrophobic fatty acid tails on the phospholipid
what is the function of cholesterol in the membrane?
increases mechanical strength and flexibility of the plasma membrane so it is less likly to get damaged. it maintains fluidity
how does cholesterol maintain fluidity of the membrane at low temps?
At low temperatures, by preventing the fatty acid tails of the membrane lipids from packing too closely together, helps to maintain the proper spacing between the lipid molecules and allows the membrane to remain flexible and functional
how does cholesterol maintain fluidity of the membrane at high temps?
At high temperatures, the lipid bilayer can become too fluid, which can also impair its function. Cholesterol stops the movement of the fatty acid tails of the membrane lipids
what is an integral protein?
a protein in the cell membrane that is fully embedded into the membrane from one side to the other
what is a channel protein?
an integral protein filled with water to allow water soluble substances to diffuses through. it is lined with hydrophillic AA and has hydrophobic AA on the outdside which interact with the fatty acid tails
name 2 types of integral proteins in the cell membranes?
carrier and channel proteins
what is a peripheral protein?
just is on one side of the membrane or the other
what is a carrier protein?
it is an integral protein which goes through a conformational change to transferre molecules from one side of the membrane to another, it used energy
what is a glycolax ?
a carbohydrate chain attached to either a lipid(glycolipid) or a protein(glycoprotein)
what are the roles of a glycoprotein?
allows cells to attach to each other, form antigens and act as receptors for hormones
what are the roles of peripheral proteins?
structural, enzymes or receptors for molecules such as hormones
what are the roles of a glycolipid?
allows for cell regognition when 2 clls come into contact with eachother, form antigens
what is the definition of diffusion?
the movement of molecules from an area of high concentration of that molecule to a low concentration
what is the definition of facilitated diffusion?
movement of molecules from an area of high concntration to low across a partially permeable membrane via integral/ transmembrane proteins
do either types of diffusion require energy?
no
where do water molecules diffuse through in the cell membrane?
specific channels called aquaporins for only water molecules
why can’t water molecules travel through the bilayer ?
they are polar and insoluble in lipids so cant diffuse through the lipid bilayer
how is a concentration gradient maintained?
molecules that pass into the cell will heighten the concentration gradient in the cell so diffusion rate will slow down and that is not what the cell wants. so by these molecules then diffusing into organelles it increases the concentration gradient
what are the 5 factors affecting simple diffusion?
temperature, diffusion distance, surface area, size of diffusing molecule and concentration gradient