cell mediated responses - t cells Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

lymphocytes

A

white blood cells involved in specific immune response

made in bone marrow

T cells mature in thymus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

step 1

A

once pathogen is destroyed by phagocytosis, the antigens are positioned on cell surface

they are now called antigen presenting cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

step 2

A

helper t cell have receptors on surface which bind to antigens on antigen presenting cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

step 3

A

once attached it activates helper t cell to divide by mitosis to replicate and make large numbers of clones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

step 4

A

cloned helper t cells differentiate into different cells

some remain as helper t cells that activate b lymphocytes

some stimulate macrophages to preform more phagocytosis

some become memory cells for shaped antigens

some become cytotoxic t cells (killer t cells)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

cell mediated t cells

A

they will only respond to antigens which are present of cells and are not antigens detached from cells of body fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

antigen presenting cells

A

any cell that presents non self antigens on its surface

infected body cells

macrophage after phagocytosis will present the antigen on the surfacce

cells of transplanted organs will have different shaped antigens on the surface compared to self cells

cancer cells - abnormal shaped self cell antigens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cytotoxic cells

A

Destroys abnormal or infected cells

Releases proteins which embeds in cell surface membrane and makes pores so any substances can enter and exit cells

Most common in viral infections

Body cells are sacrificed to prevent viral replication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly