Cell division, Cell diversity and Cellular organisation Flashcards
3 phases of cell cycle
interphase, mitotic phase, G0 phase
interphase
time of growth and preparation for cellular division
DNA replicated and checked for errors
protein synthesis in cytoplasm
chloroplast and mitochondria grow in number
stages of interphase
g1- growth phase(organelles produced and replicate
S- DNA replication
g2- second growth phase continued growth in size and DNA checked for error
miotic phase
mitosis- nucleus divides
cytokinesis - cytoplasm divides
G0
cell leaves cycle temporarily or permamently
differentiation- cell specialised to carry out a function can no longer divide
DNA might be damaged so it enters arrrest apoptosis
how do chromosomes act in mitosis
DNA molecules converted into two identical DNA molecules called chromatid joined together by the centromere
important to be kept together to be precisely manoeuvred/ segregated
what is the importance of mitosis
ensures both daughter cells are genetically identical to the parent cells, they will have the exact copy of DNA in present cells and the same number of chromosomes
growth, repair, asexual reproduction
how is the cell cycle controlled
checkpoints are done to ensure the cell is process of each phase has been accurately completed
G1check point- end of g1 phase makes sure cell has met requirements
G2check point- at the end of the G2 phase(checks DNA has been replicated properly and cell begins mitosis
spindle checkpoint- makes sure all of the chromosomes are correctly attached to the spindles
what are the stages of mitosis
prophase, metaphase, anaphase and telophase
they are all interlinked and work between themselves
Prophase
chromatin condenses and becomes visible and nuclear membrane breaks down
microtubules form spindle shaped structures linking poles of the cell
centrioles migrate to the poles of cell to help the formation of the spindle fibres
the spindle fibres attach to parts of the chromosomes and move to metaphase plate
at the end nuclear envelope has disappeared
metaphase
chromosomes moved by the spindle fibres to the metaphase plate and lined upheld in position
Anaphase
The spindle fibres attach to the centromeres of the chromosome on both sides and splits it in two, fibres contract and pull the chromatids to each side of the cell
telophase
Once the chromatids reach the poles they are called chromosomes, new sets of chromosomes assemble at the poles and the nuclear envelope forms around them, chromosomes uncoil and nucleolus forms
cytokinesis
actual splitting of the membrane into two different cells
animal cytokinesis
cleavage furrow forms around middle of the cell membrane pulled inwards until it can fuse with itself and pinch of into two
plant cell cytokinesis
cell wall stops cleavage furrow, so vesicles from the Golgi apparatus assemble at the metaphase plant all using together until the cell is split into two and new cell walls form around the membranes
what type of chromosomes are made in mitosis
diploid
what type of chromosomes are made in meosis
haploid
what are homolgus chromosomes
chromosomes from each parent that have the same matching genes(pair) for each characteristic)
same genes in the same posititns
Allele?
different versions of the same gene eg the gene for eye colour varies blue/ brown eyes
what are the stages of meiosis
meiosis 1- reduction division when the pairs of chromosomes are separated in two cells
meiosis 2- second division pair of chromosomes are separated forming 2 more cells 4 haploid daughter cells in total
Meiosis 1(p1)
-chromosomes condense nuclear envelope/ nucleolus disappears
-spindle fibres begin to form
-homologous chromosomes pair up (bivalents)
-chromosomes are large molecules and as they move around in cytoplasm they get entangled and DNA crosses over
Meiosis1(m1)
homologous pairs of chromosomes assemble on the metaphase plate
assembly of the homologous chromosomes on the metaphase plate is random maternal/ paternal chromosomes can end up facing either pole(independent assortment)
Meiosis1(anaphase 1)
homologous chromosomes pulled apart but the chromatid stay together