Cell Division

Question 0

Centromere

Answer 0

Point of close contact of sister chromatids

Question 1

Sister chromatids

Answer 1

Paired copies of chromosomal DNA. Intentional copies of genetic information

Question 2

4 phases of cell cycle

Answer 2

1) . G1 phase - general function and metabolism
2) . S phase - DNA replication
3) . G2 phase - waiting for chromosome segregation
4) . Mitotic phase - segregation of replicated chromosomes

Question 3

Centrioles

Answer 3

Two organising centres

Question 4

Aster

Answer 4

Radiating micro tubules that position centrioles

Question 5

Microtubules

Answer 5

Protein ropes

Question 6

Microtubules

Answer 6

Protein ropes

Question 7

Kinetochore

Answer 7

Attachment linking micro tubules to centromere

Question 8

Centrosome

Answer 8

Mitotic centre

Question 9

Cell cycle clock

Answer 9

Speed and timing of cell decision is controlled by synchronising molecular cycle

Question 10

Checkpoints

Answer 10

Ensure that cycle does not progress until all preceding functions complete
G1/S G2/M and M

Question 11

Cyclin dependent kinases

Answer 11

Enzymes which adds phosphates to downstream molecules

Question 12

Cyclins

Answer 12

Regulator proteins that activate CdKs. Produced in response to signals

Question 13

Maturation promoting factor

Answer 13

Controls G2/M checkpoint

Question 14

Cancer cells

Answer 14

Loss of cell cycle control. Do not obey regulatory signals, cell division is not limited

Question 15

Cancer occurs when

Answer 15

Malignant cells form tumours blocking organ function

Question 16

What causes cancer cells to lose cell cycle control?

Answer 16

Lose anchorage dependence and density dependent inhibition

Question 17

Karyotypes

Answer 17

Are aligned sets of chromosome from a cell