cell division Flashcards
what is the phase of the cell growth cycle in which the cell spends most of its time in?
interphase
Once the cell has grown enough, it begins to replicate its DNA in the _ phase
S
how does the cell prepare itself for division through?
mitosis
how does the cell split itself into daughter cells through?
cytokinesis
what is the cycle of growth and division called?
cell cycle
what are the 4 phases of the cell cycle?
G1
S
G2
M
what phases encompass interphase?
G1
S
G2
what phase occurs right after mitosis?
G1
what is the purpose of the G1 phase?
acts as a gap for the cell before needing to replicate its DNA and prepare again for cell division
what is the S phase know for?
synthesis of DNA
what happens during the S phase?
cell doubles its DNA in preparation for division
what is the gap between the S and M phase?
G2 phase
what is the M phase?
mitosis
what is the G0 phase?
cell becomes senescent, cell doesn’t grow or synthesize more DNA and remains “asleep” until it rejoins the cycle
what is the restriction point?
cell cycle checkpoint that occurs in G1 of the cell cycle in animal cells
The “commitment” step of this restriction point involves the formation of ___________________ that allow the cell to move on to the next phase.
cyclin/CDK complexes
what cyclin/CDK complexes form in the G1 phase?
S-phase cyclin complexes
what cyclin/CDK complexes form in the G2 phase?
M-phase cyclin/CDK complexes.
which checkpoint prevents the cell from going into mitosis before DNA synthesis has been completed?
unreplicated DNA checkpoint
what checkpoint makes sure that the newly replicated DNA has maintained its integrity?
G2 DNA-damage checkpoint
in which phase is there a spindle assembly and chromosome segregation checkpoint?
M phase
what is the purpose of cyclin/CDK complexes?
proteins come together and form a functional enzyme that can then modify downstream target proteins, helping the cell progress through the cell cycle.
list the cyclins and CDKs associated with the G1 phase
cyclin D
CDK 4
CDK 6
list the cyclins and CDKs associated with the S phase
cyclin E
cyclin A
CDK 2
list the cyclins and CDKs associated with the G2 phase
cyclin A
CDK 1
list the cyclins and CDKs associated with the M phase
cyclin B
CDK 1