Cell Death and Perfusion Disorders II Flashcards
what is a thrombus
blood clot
what is an embolus
piece of free-floating foreign material in the blood
thromboembolus
an embolus derived from a thrombus
watershed area
a region of the body that receives dual blood supply from the distal branches of two large arteries
end-artery
an artery that is the only supply of oxygenated blood to a portion of a tissue
examples of tissues that receive end-artery supply
regions of kidney, spleen, liver, intestine, heart, brain
sequela
condition that is a consequence of a previous disease or injury
amorphous
no clearly defined shape or form
what percentage of body weight is water
60%
what is the distribution of water in the intracellular and extracellular environment
2/3 intra
1/3 extra
what is the distribution of plasma and interstitial fluid
80% interstitial; 20% plasma
causes of edema (4)
- increased MICROvascular permeability
- increased hydrostatic pressure inside vessels
- decreased oncotic pressure inside vessels
- decreased lymphatic drainage
causes of increased HP inside vessels
hyperemia or congestion
causes of decreased OP inside vessels
decreased production of or excessive loss of albumin
gross morphology of edema
swelling of tissues; extra fluid in a cavity; can be clear or yellow
histologic morphology of edema
amorphous, pale eosinophilic fluid
how does pulmonary edema appear
foamy
edema in the chest cavity is called
hydrothorax
edema in the abdominal cavity is called
ascites
what region of tissue will get edema first
subcutaneous layer (takes path of least resistance)
what are two consequences of edema
fibrosis and compression of the organs in the space the fluid occupies
severity of edema depends on (2)
duration and location
what is hyperemia
increase in blood supply to an organ or tissue
what does hyperemia indicate
an adaptive circulatory response (increased oxygen demand, inflammation, heat dissipation)
