Cell Cycle & Mitosis Flashcards
Define the principles of cell division
- Cell division involves the parent cell dividing to create two identical daughter cells
- Not all cells divide
- Cell division is regulated by a series of complex sequence of events
Describe why cells divide
- It is used to grow new tissue and replace damaged or dead cells
- There are two types of cell division: Mitosis & Meiosis
- Mitosis is the division of somatic (body) cells
- Meiosis is the division of gamete (sex cell) production
The cell cycle can be divided into what two phases?
- Interphase
- Mitotic phase
List the phases of cell division
- Interphase which includes G0, G1, S phase and G2
- Mitotic phase which includes:
▫ Prophase
▫ Metaphase
▫ Anaphase
▫ Telophase
What is the purpose of cell cycle check points?
To ensure the cell is fit to progress to the next phase, this avoids unhealthy/incomplete cells from dividing
What occurs during mitosis
The division of the nucleus
What occurs at G0 phase?
Normal cell functions - no division
What occurs at G1 phase?
Replication of most organelles and cellular components
What occurs at S phase?
Replication of DNA and synthesis of a new set of chromosomes
What occurs at G2 phase?
Enzyme and centrisome replication completed as cell is prepared for division
Explain the process of DNA replication
- The enzyme helicase unwinds the strands of DNA creating two separate strands
- The enzyme primase builds RNA primers onto the existing DNA strands to give DNA polymerase a place to start building new DNA strands
- DNA polymerase catalyses the addition of free nucleotides to the growing new DNA strands
- The result of this is two identical double helices