Cell Cycle & Mitosis Flashcards

1
Q

Define the principles of cell division

A
  • Cell division involves the parent cell dividing to create two identical daughter cells
  • Not all cells divide
  • Cell division is regulated by a series of complex sequence of events
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2
Q

Describe why cells divide

A
  • It is used to grow new tissue and replace damaged or dead cells
  • There are two types of cell division: Mitosis & Meiosis
  • Mitosis is the division of somatic (body) cells
  • Meiosis is the division of gamete (sex cell) production
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3
Q

The cell cycle can be divided into what two phases?

A
  • Interphase

- Mitotic phase

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4
Q

List the phases of cell division

A
  • Interphase which includes G0, G1, S phase and G2
  • Mitotic phase which includes:
    ▫ Prophase
    ▫ Metaphase
    ▫ Anaphase
    ▫ Telophase
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5
Q

What is the purpose of cell cycle check points?

A

To ensure the cell is fit to progress to the next phase, this avoids unhealthy/incomplete cells from dividing

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6
Q

What occurs during mitosis

A

The division of the nucleus

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7
Q

What occurs at G0 phase?

A

Normal cell functions - no division

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8
Q

What occurs at G1 phase?

A

Replication of most organelles and cellular components

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9
Q

What occurs at S phase?

A

Replication of DNA and synthesis of a new set of chromosomes

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10
Q

What occurs at G2 phase?

A

Enzyme and centrisome replication completed as cell is prepared for division

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11
Q

Explain the process of DNA replication

A
  • The enzyme helicase unwinds the strands of DNA creating two separate strands
  • The enzyme primase builds RNA primers onto the existing DNA strands to give DNA polymerase a place to start building new DNA strands
  • DNA polymerase catalyses the addition of free nucleotides to the growing new DNA strands
  • The result of this is two identical double helices
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