Cell Cycle Control Flashcards
1
Q
draw CDK activity control diagram
A
2
Q
Cdc25 overexpression cells are:
A
small (shorter G2)
3
Q
Cdc25+ activates this complex
A
Cdc2/Cdc13
4
Q
wee1- mutants cells are:
A
small (short G2)
5
Q
cells are larger when Wee1+ is overexpressed due to:
A
prolonged G2
6
Q
activity of this is constant throughout cell cycle
A
CDK
7
Q
Cdc13+/cyclin forms a complex with:
A
Cdc2/Cdk
8
Q
protein Y-kinase that phosphorylates Cdc2/Cdk on Y15
A
Wee1
9
Q
affect of Wee1 phosphorylation of Cdc2/Cdk
A
inhibition
10
Q
protein phosphorylates T161 on Cdc2
A
CDK Activating Kinase
11
Q
protein phosphatase removes phosphate group from Cdc2/Cdk
A
Cdc25
12
Q
Cdc25 removes phosphate group from:
A
Y15
13
Q
diagram CLN1 regulation of G1 cyclins
A
14
Q
A
