Cell Cycle And Cell Division Flashcards
During the division of cell , ______ and ______ also takes place .
DNA replication
Cell growth
Although ______ is a continuous process , _____ occurs only during one specific stage in the cell cycle .
Cell growth
DNA synthesis
Cell growth in terms of _______is a continuous process .
Cytoplasmic increase
A typical eukaryotic human cell has a cell cycle of _____hours .
24
Cell cycle of yeast lasts for about -
90 minutes
The 2 basic phases of cell cycle -
Interphase
M Phase /Mitosis
In the average life cycle of 24 hours , cell division proper lasts for only about -
1 hour
The ______ lasts for more than 95% of the duration of the cell cycle .
Interphase
M phase of cell cycle starts with the _______division called ____ .
Nuclear
Karyokinesis
Division of cytoplasm called ______ occurs after karyokinesis .
Cytokinesis
During interphase , the cell is undergoing both ______ and _____ in an orderly manner .
Cell growth
DNA replication
Interphase is divided into -
3 sub phases -
G1
S
G2
______ phase corresponds to the interval between mitosis and DNA replication .
G1
During G1 phase , the cell is ________and _______ but DOES NOT REPLICATE ITS DNA .
METABOLICALLY ACTIVE
CONTINUOUSLY GROWS
S phase marks the period during which _______ takes place .
DNA synthesis or replication
During S phase , the amount of ______ per cell doubles .
DNA
During S phase , there is no increase in _______ .
Chromosome number .
At G1 , if the cell had 2n chromosomes , then after S phase , the number will still be 2n .
In animal cells , during the S phase , DNA replication begins in the _______ and the _______ duplicates in the cytoplasm .
Nucleus
Centriole
During G2 phase , _____ are synthesised in preparation for mitosis while ________ continues .
Proteins
Cell growth
Some cells in animals do not appear to exhibit division . Example-
Heart cells
The cells that do not divide further ______ G1 phase to enter an INACTIVE stage called QUIESCENT STAGE (G0).
Exit
G0 stage is achieved when cells exit ______.
G1
Cells in this stage remain metabolically active but no longer proliferate unless called on to do so .
Quiescent stage
In ______ , mitotic division is only seen in diploid somatic cells . Against this , ________ can show mitosis in both HAPLOID and DIPLOID cells .
Animals
Plants
Exception of a animal where mitosis is seen in haploid cells .
Male honey bees
This is the most dramatic period of the cell cycle , involving a major reorganisation of virtually all components of the cell .
M phase - mitosis
Since the number of ________ in the parent and the progeny is same , mitosis is also called _________.
equational division
Mitosis has beeen divided into 4 stages of ______ division .
Nuclear -karyokinesis
Prophase of mitosis follows ___ phases of interphase .
S and G2
In ______phases the new DNA molecules formed are not distinct but intertwined .
S and G2
Prophase is marked by the initiation of _______ .
Condensation of chromosomal materials
The centrosome which had undergone duplication in the ______ phase , begins to move towards opposite poles in prophase .
S phase
Completion of prophase is marked by -
Late prophase
Chromosomal material condenses to form chromosomes
Chromosomes are composed of 2 chromatids joined at the centromere .
Centrosomes move to opposite poles .
2 asters along with spindle fibres form mitotic apparatus .
During late prophase , each _______ radiates out MICROTUBULES called ASTERS .
Centrosome
Mitotic apparatus consists of -
2 asters together with spindle fibres
Disappearance of organelles occurs during late/early prophase .
Late
Difference between early and late prophase .state different events .
Early - initiation of chromosome condensation ; centrosome moves to opposite poles
Late- compact chromosomes formed wth sister chromatids joined at centromere ; centrosome radiates out asters ; organelles disappear ( including nucleolus and nuclear envelope )
Nucleolus and nuclear envelope disappears during -
Late prophase ( end )
______ marks the start of 2nd phase of mitosis - metaphase .
Complete disintegration of nuclear envelope
In _____ phase , chromosomes are spread throughout the cytoplasm of the cell .
Metaphase
By this stage , condensation of chromosomes is completed and they can be observed clearly under the microscope .
Metaphase
Metaphase is the best stage to study the _______ of chromosomes .
Morphology
_______ chromosome is made up of 2 sister chromatids joined at the centromere .
Metaphase
Small disc shaped structures on the surface of centromeres are called _____ ans they can be seen in ________ phase .
KINETOCHORES
Metaphase - for attachment of spindle
KINETOCHORES are formed by __________ during ________ phase
Spindle fibres
Metaphase
______ serve as sites of attachment of spindle fibres .
KINETOCHORES
_______ phase is characterised by on chromatids of each chromosome connected by its kinetochore to spindle fibres from one pole and its sister chromatid connected by its kinetochore to spindle fibres from opposite pole .
Metaphase
Arranged at equator
The plane of allignment of the chromosomes at metaphase is referred to as ______ .
Metaphase plate
Features of metaphase -
Spindle fibres attach to KINETOCHORES of chromosomes .
Chromosomes aligned at the equator
During anaphase , daughter chromatids are referred to as __________.
Daughter chromosomes of the future nuclei
What happens in early anaphase ?
Each chromosome is split simultaneously and the 2 daughter chromatids migrate towards opposite poles .
As each chromosome moves away from the equatorial plate , the _______ of each chromosome remains directed towards the POLE and hence at the LEADING EDGE , with the _______ of the chromosome trailing behind .
Centromere
Arms
Chromatids move to opposite poles during late/early anaphase .
Late
Early - chromatids separate
At the beginning of telophase , _______ that have reached opposite poles DECONDENSE and ___________ .
Chromosomes
Lose their individuality
Decondensation of chromosomes occurs in early /late telophase .
Early
In early telophase , individual chromosomes can no longer be seen and a set of ________ tends to collect at each pole
Chromatin material
Nucleolus , Golgi complex and ER reform in -
Late telophase
Segregation of duplicated chromosomes into daughter nuclei is called -
Karyokinesis
In an animal cell ,cytokinesis is achieved by the appearance of a ________ in the ________ .
Furrow
Plasma membrane
Formation of a furrow in animal cell is from ______ to _______ .
Inside/outside
Outside to inside
Centripetal
In plant cells , wall formation starts in the _______ of the cell and grows ______ to meet the existing lateral walls .
Centre
Outward
( centrifugal )
Formation of a new ________ begins with the formation of a simple precursor called the CELL PLATE in plant cells .
Cell wall
The cell plate ( precursor of cell wall ) in plat cells represents ______ between the walls of the two adjacent cells .
Middle lamella
At the time of CYTOPLASMIC DIVISION , organelles like ______ and ______ get distributed between the 2 daughter cells .
Mitochondria
Plastid
In some organelles ______ is not followed by _______ , as a result of MULTINUCLEATE condition arises .
Karyokinesis
Cytokinesis
The multinucleate condition leads to the formation of ________.
Syncytium
Liquid endosperm in coconut
Mitosis is usually restricted to the ______ cells only .
Diploid
In some ____ and some social ______ haploid cells also divide by mitosis .
Lower plants
Social insects
The growth of ________ organisms is due to mitosis .
Multicellular
Cell growth results in disturbing the ratio between _____ and ______.
Nucleus
Cytoplasm
It becomes essential for the cell to divide and restore the ______ ratio , when it is disturbed due to cell GROWTH .
Nucleo-cytoplasmic ratio
Meiosis insures the production of _____ phase in the life cycle of sexually reproducing organisms .
Haploid
________ restores DIPLOID phase in the life cycle of sexually reproducing organisms .
Fertilisation
We come across meiosis during _______ in plants and animals .
Gametogenesis
Meiosis involves 2 sequential cycles of ____ and _______ but only a single cycle of _________.
Nuclear division
Cell division
DNA replication
DNA replication occurs how many times in meiosis ?
1
Meiosis 1 is initiated after the parental chromosomes have replicated to produce identical sister chromatids at the _______ phase .
S
Meiosis involves pairing of ______ chromosomes .
Homologous
Meiosis involves RECOMBINATION between _______.
Non-sister chromatids of homologous chromosomes
4 haploid cells are formed at the end of ______.
Meiosis 2
Meiosis I is initiated at the ______ phase .
S
When sister chromatids are formed from chromosomes
Prophase of ______ is typically LONGER and MORE COMPLEX as compared to prophase of ______ .
Meiosis 1
Mitosis
Prophase 1 of meiosis 1 is subdivided into 5 phases based on -
Chromosomal behaviour
5 subdivisions of prophase 1 :
Leptotene Zygotene Pachytene Diplotene Diakinesis
Prophase of the first meiotic division is typically _______ and ________ when compared to prophase of MITOSIS .
Longer
More complex
During ___ stage , chromosomes become gradually visible under a light microscope .
Leptotene
The compaction of chromosomes continues through _______.
stage of prophase 1
Leptotene
What happens during the first phase of prophase 1 ?
Leptotene - compaction of chromosomes continues
Leptotene is followed by -
Zygotene
During ______ , chromosomes starts pairing together . ( stage of prophase 1 )
Zygotene
Pairing of chromosomes is called ______ and occurs during _____ .
Synapsis
Zygotene
Such paired chromosomes as seen during ZYGOTENE after synapsis are called ________ .
Homologous chromosomes
ELECTRON MICROGRAPHS of this stage indicate that synapsis is accompanied by the formation of complex structure called SYNAPTONEMAL COMPLEX .
Zygotene
The complex formed by a pair of SYNAPSED HOMOLOGOUS CHROMOSOMES is called a _______ or _____ .
Bivalent
Tetrad
Bivalent or tetrad formed in zygotene are clearly visible during which stage ?
Pachytene - visible
Zygotene - formed
The ______ stages of prophase 1 are relatively shorter as compared to PACHYTENE .
1st two - leptotene and zygotene
Homologous chromosomes are formed during _______ (stage of prophase 1)
Zygotene
Synapsis -> homologous chromosomes ->synaptonemal complex -> bivalent /tetrad
During this stage pf prophase 1 , 4 CHROMATIDS of each bivalent chromosomes become distinct and clearly appear as TETRAD ( bivalent )
Pachytene
Pachytene phase is characterised by the appearance of __________ .
Recombination nodules
What are recombination nodules and and when do they appear ?
Sites at which crossing over occurs between non-sister chromatids of homologous chromosomes .
They appear during pachytene
– – – – –Is the exchange of genetic material between two homologous chromosomes .
Crossing over
Crossing over is also an – – – – – mediated process and The enzyme involved is called – – – – – .
Enzyme -mediated
Recombinase
________ leads to recombination of genetic material on the 2 chromosomes .
Crossing over .
_______ is an enzyme-mediated process .
Crossing over - recombination
________ is completed at the end of PACHYTENE .
Recombination between HOMOLOGOUS chromosomes
Recombination occurs during _______ , leaving the chromosomes linked at the sites of CROSSING OVER .
Pachytene
The beginning of ________ is recognised by the DISSSOLUTION of SYNAPTONEMAL complex .( stage of prophase 1)
Diplotene
_______ is recognised by the tendency of the RECOMBINED homologous chromosomes of the BIVALENTS to separate from each other except at the sites of cross overs .
Diplotene
X -shaped structures called CHIASMATA are formed during -
Diplotene
Longest stage of prophase 1 -
Diplotene - can last for months or years in oocytes of some vertebrates
Which stage of prophase 1 can last for months or years in the OOCYTES OF SOME VERTEBRATES ?
Diplotene
The final stage of meiotic prophase 1 is -
Diakinesis
________is marked by terminalisation of chiasmata
Diakinesis
Diplotene is characterised by ______ and diakinesis is recognise by ______.
Dissolution of synaptonemal complex
Terminalisationof chiasmata
During this phase of prophase 1 , chromosomes are fully condensed and the meiotic spindle is assembled to prepare the homologous chromosomes for separation .
Diakinesis
During diakinesis , _______ is assembled to. Prepare the homologous chromosomes for separation .
MEIOTIC spindle
What happens at the end of diakinesis ?
Nucleolus disappears and nuclear envelope also breaks down
_______ stage of prophase 1 represents transition to metaphase 1.
Diakinesis
During which phase of meiotic prophase 1 , homologous chromosomes are prepared for separation ?
Diakinesis
The ______ chromosomes align on the equatorial plate during metaphase 1 of meiosis 1 .
Bivalent
During metaphase 1 MICROTUBULES from the opposite poles of the spindle attach to the KINETOCHORE of ________.
Homologous chromosomes
During metaphase 2 of meiosis 2 , MICROTUBULES from the opposite poles of the spindle get attached to the KINETOCHORE of _________.
Sister chromatids
During _______ of meiosis , HOMOLOGOUS CHROMOSOMES separate , while sister chromatids remain associated at their centromeres .
Anaphase 1
Dyad of cells appears in ______ stage .
Telophase 1 of meiosis 1
Tetrad of cells appear in _______.
Telophase 2 of meiosis 2
During telophase 1 , _________ and ________reappear and ________ follows .
Nuclear membrane
Nuceolus
Cytokinesis
During telophase 1 , nucleolus and nuclear membrane reappears , cytokinesis follows and this is called as ________ .
Dyad of cells
The stage between 2 meiotic divisions is called _______.
Interkinesis
Interkinesis is generally _____ lived .
Short
Interphase - long
There is replication of DNA during interkinesis . T/F
F . No replication of DNA during interkinesis as against that of interphase
Interkinesis is followed by -
Prophase 2
Which is simpler - prophase 1 or 2 of meiosis .?
2
Meiosis 2 is initiated immediately after -
Cytokinesis , usually before chromosomes have fully elongated .
meiosis 1/ 2 resembles a normal mitosis .
2
What happens by the end of prophase 2 ?
Nuclear membrane disappears
Chromosomes again become compact
Pairing = - ———- And it occurs in which phase ?
Synapsis
Zygotene
Definition of synapsis and crossing over ?
Synapsis - formation of homologous chromosomes . Zygotene
Crossing over - exchange of genetic material between 2 homologous chromosomes. Pachytene
Crossing over = - ——- and it occurs in ?
Recombination
Pachytene
Non -sister chromatids are involved in -
Homologous chromosomes are involved in -
Recombination -crossing over
Synapsis - pairing
Bouquet stage occurs in which stage of prophase 1 ?
Leptotene
Part of plant suitable for the study of meiosis -
Anther
In meiosis , how many cycles of chromosomal division occurs ?
1